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Pharmaceutical Intermediate
Professional Supply CAS 134678- 17 -4 Lamivudine
Model NO.
TY-02ALI
Einecs
603-844-3
Shelf
2 Years
Assay
99%
Appearance
White Powder
CAS No.
134678-17-4
Transport Package
25kg/Drum 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
$ 1.80 - 4.50
Contact Us
Description
Product Description
Product name
Lamivudine
CAS
134678-17-4
Appearance
white powder
Assay
99%
Storage
Cool and Protect from light
Product Name:Lamivudine
CAS:134678-17-4
MF:C8H11N3O3S
MW:229.26
EINECS:603-844-3
Mol File:134678-17-4.mol
Melting point:177 °C
alpha D21 -135° (c = 0.38 in methanoll)
Boiling point:475.4±55.0 °C(Predicted)
Density 1.73±0.1 g/cm3(Predicted)
refractive index -142 ° (C=1, MeOH)
Flash point:9ºC
storage temp. Freezer
solubility water: soluble10mg/mL, clear
pka13.83±0.10(Predicted)
form powder
color white to beige
Water Solubility 70g/L(temperature not stated)
Uses
1. Antiviral drugs for hepatitis
2. Antiviral drugs for the treatment of liver and gallbladder diseases.
3. Medicine for liver and gallbladder diseases.
DescriptionLamivudine is a new generation orally active nucleoside analog launched in the U.S.A. for use in combination with zidovudine (AZT) as a first-line therapy for patients with HIV infection. Lamivudine is rapidly converted to phosphorylated metabolites in the body which act as inhibitors and chain terminators of HIV reverse transcriptase (RT), the enzyme required for the replication of the HIV genome. Lamivudine has similar inhibitory potency to RT as AZT but is 10 times less toxic and is active against AZT-resistant strains of HIV. Combination therapy of lamivudine and AZT produced a large decrease in blood-borne virus with an increase in CD4 cells, an effect that can be sustained for 2 years. Since hepatitis B virus (HBV) also encodes a polymerase with a RT function necessary for the conversion of a RNA replicative intermediate to DNA, clinical efficacy has been reported for lamivudine in treating patients with HBV infection. It was reported that the enantiomer of lamivudine is equipotent against HIV but with considerably higher cytotoxicity.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.
Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.
Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.
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