Etomidate is a carboxylated intended for the inductionof general anesthesia. It is marketed as the morepotent R (+) isomer. It is believed to exert its anestheticeffect via positive modulation of the GABAA receptor. Itis not water soluble and is available in the United States as a2-mg/mL solution containing 35% v/v glycol andin Europe as a soybean oil and medium-chain triglyceridesformulation. The glycol has been associatedwith moderate-to-severe pain on injection and irritation ofthe vascular tissue. A high incidence of skeletal musclemovements were noted in about 32% of patients followingetomidate injection. Case reports of seizures are also foundin the literature.
Product Name: | Etomidate |
MOQ | 1KG |
CAS: | 33125-97-2 |
MF: | C14H16N2O2 |
MW: | 244.29 |
EINECS: | 251-385-9 |
Formulations containing etomidate are used for general anesthesia and sedation.1 Etomidate also inhibits adrenal cortisol biosynthesis and mitigates hypercortisolism, as is found in Cushing syndrome.2,3 This product is intended for research and forensic applications.
Usage
Short-time intravenous anesthetics.
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