Quick detail:
Name: | Gefitinib |
CAS No.: | 184475-35-2 |
Formula: | C22H24ClFN4O3 |
Molecular Weight: | 446.90 . |
Synonyms: | N-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;ZD1839;4-(3-Chloro-4-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline; Irressat;Gefitinib (JAN/USAN);4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-;ZD 1839;4-Quinazolinamine, |
Density: | 1.322 g/cm3 |
Melting Point: | 119-120 °C |
Boiling Point: | 586.8 °C at 760 mmHg |
Flash Point: | 308.7 °C |
Appearance: | light-yellow crystalline powder |
Description :
Gefitinib is a type of drug called a tyrosine kinase inhibitor (TKI), also known as a cancer growth inhibitor. Kinases are proteins in the body that regulate how the cells grow and divide. Gefitinib blocks (inhibits) the protein from sending signals to the cancer cells that make them grow and divide.
For the treatment of locally advanced or metastatic non-small cell lung cancer, after failure of both platinum-based and taxane-based chemotherapies.Note: If a drug has been approved for one use, physicians may elect to use this same drug for other problems if they believe it may be helpful.
COA:
Product name | Gefitinib | ||
CAS No. | 184475-35-2 | Outer Packing | 1KG |
Production date | May,05,2016 | Shelf life | May.04,2023 |
Standard adopted | house standard | ||
Items of analysis | Specification | Results | |
Appearance | White to off-white powder | off-White powder | |
Identifcation | HPLC(RT) | Complies | |
Loss on drying | ≤ 0.5% | 0.13% | |
Residue on ignition | ≤0.,1% | 0.1% | |
Max Single Impurity | ≤ 0.10 % | 0.09% | |
Total Impurity | ≤.1.0% | 0.24% | |
Purity(HPLC) | ≥99% | 99.76% | |
Conclusion | Qualified |
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