CD91 (Phospho S4520) Polyclonal Antibody

Model NO.
BS64564
Specification
100ug/1mg
Trademark
Bioworld
Origin
China
Production Capacity
3000 Vials
Reference Price
$ 222.75 - 247.50

Product Description

Catalog No. BS64564
Product Name CD91 (Phospho-S4520) polyclonal antibody
Applications WB
Alternative Name LRP-1; A2MR; APOER; CD91; LRP1; Msi 1; Msi1; MSI1H; Musashi homolog 1; Musashi-1; Musashi1; RNA binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 1
Swiss-Prot Q07954
Host Rabbit
Reactivity Human,Mouse,Rat
Application_all WB: 1:500~1:1000 IHC: 1:50~1:200
Product Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity CD91 (Phospho-S4520) polyclonal antibody detects endogenous levels of CD91 protein only when phosphorylated at Ser4520.
BiowMW ~ 85 kDa
Note For research use only, not for use in diagnostic procedure.
Immunogen Synthetic phosphopeptide derived from human CD91 around the phosphorylation site of Serine 4520.

  • Western blot (WB) analysis of CD91 (Phospho-S4520) polyclonal antibody at 1:500 dilution LaneA:The Brain tissue lysate of Rat LaneB:C6 whole cell lysate LaneC:L02 whole cell lysate LaneD:HEK293T whole cell lysate

Background

Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary. CD91 (Phospho S4520) Polyclonal Antibody
CD91 (Phospho S4520) Polyclonal Antibody CD91 (Phospho S4520) Polyclonal Antibody CD91 (Phospho S4520) Polyclonal Antibody

 

PNEUTEC.IT, 2023