CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody

Model NO.
BS2040
Certification
CE, ISO9001
Host
Rabbit/Mouse
Reactivity
Human, Mouse, Rat
Transport Package
Refrigerated Transport
Specification
100ug/1mg
Trademark
Bioworld
Origin
China
HS Code
300219000
Production Capacity
3000 Vials
Reference Price
$ 222.75 - 247.50
Contact Us

Product Description

Catalog No. BS2040
Product Name CBP80 (R5) polyclonal antibody
Applications WB IHC
Alternative Name Nuclear cap-binding protein subunit 1; 80 kDa nuclear cap-binding protein; CBP80; NCBP 80 kDa subunit; NCBP1; CBP80; NCBP
Swiss-Prot Q09161
Host Rabbit
Reactivity Human,Mouse,Rat
Application_all WB: 1:500~1:1000 IHC: 1:50~1:200
Product Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity CBP80 (R5) polyclonal antibody detects endogenous levels of CBP80 protein.
BiowMW ~ 88 kDa
Note For research use only, not for use in diagnostic procedure.
Immunogen Synthetic peptide, corresponding to the N-terminus of Human CBP80.

  • Western blot (WB) analysis of CBP80 (R5) pAb at 1:500 dilution Lane1:K562 whole cell lysate(10ug) Lane2:Hela whole cell lysate(20ug) Lane3:The Brain tissue lysate of Mouse(40ug) Lane4:The Brain tissue lysate of Rat(40ug)

  • Immunohistochemistry (IHC) analyzes of CBP80 (R5) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

  • Western blot (WB) analysis of CBP80 (R5) pAb pAb at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:MCF-7 whole cell lysate(40ug) Lane3:The Brain tissue lysate of Rat(40ug) Lane4:The Brain tissue lysate of Mouse(40ug)

Background

In eukaryotes, the majority of mRNAs have an m(7)G cap, which is added cotranscriptionally and plays a critical role in many aspects of mRNA metabolism. The effect of the cap on translation is mediated by the initiation factor eIF-4F, whereas the effect on pre-mRNA splicing involves a nuclear complex(CBC). CBC consists of two cap binding proteins CBP20 and CBP80, which mediate the stimulatory functions of the cap in pre-mRNA splicing, 3' end formation and U snRNA export. The genes CBC1 and CBC2 encode CBP80 and CBP20, respectively. CBP80 comprises three domains, each containing a MIF4G domain. CBP20 has an RNAP fold and associates with the second and third domains of CBP80. CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody



CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody CE, ISO9001 Approved Cbp80 (R5) Polyclonal Antibody

 

Biological Products

PNEUTEC.IT, 2023