CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody

Model NO.
BS2078
Host
Rabbit/Mouse
Reactivity
Human, Mouse, Rat
Certification
CE, ISO9001
Transport Package
Refrigerated Transport
Specification
100ug/1mg
Trademark
Bioworld
Origin
China
HS Code
300219000
Production Capacity
3000 Vials
Reference Price
$ 222.75 - 247.50
Contact Us

Product Description

Catalog No. BS2078
Product Name DGK-δ (S66) polyclonal antibody
Applications WB IHC IF
Alternative Name Diacylglycerol kinase delta; DAG kinase delta; 130 kDa diacylglycerol kinase; Diglyceride kinase delta; DGK-delta; DGKD; KIAA0145; DGKδ; DGK δ
Swiss-Prot Q16760
Host Rabbit
Reactivity Human,Mouse,Rat
Application_all WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Product Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity DGK-δ (S66) polyclonal antibody detects endogenous levels of DGK-δ protein.
BiowMW ~ 135 kDa
Note For research use only, not for use in diagnostic procedure.
Immunogen Synthetic peptide, corresponding to amino acids 34-88 of Human DGK-δ.

  • Western blot (WB) analysis of DGK-δ (S66) pAb at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:Hela whole cell lysate(40ug) Lane3:A2780 whole cell lysate(40ug) Lane4:PC12 whole cell lysate(40ug) Lane5:3T3-L1 whole cell lysate(40ug)

  • Immunohistochemistry (IHC) analyzes of DGK-δ (S66) pAb in paraffin-embedded human Rectum carcinoma tissue at 1:50.showing cytoplasmic staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Background

Diacylglycerol kinases (DGKs) phosphorylate diacylglycerol (DAG) to produce phosphatidic acid. DAG and phosphatidic acid are lipids that act as second messengers in signaling cascades. DGK-α influences cell activation and secretion of lethal exosomes, which in turn control cell death. DGK-β is abundant in restricted brain regions such as the caudate putamen and olfactory tubercle. DGK-γ encodes full-length and truncated transcripts that are present in a range of human tissues, with greatest expression observed in retina. DGK-δ is most abundant in skeletal muscle. DGK-ε shows specificity for arachidonylcontaining diacylglycerol and is expressed predominantly in testis. DGK-θ is most abundant in the cerebellum and hippocampus. DGK-ι is present in brain and retina as a predominant transcript of more than 12 kb, including a long 3-prime untranslated region, with additional low abundance transcripts of 9.5 and 7.5 kb. DGK-η is closely related to DGK-δ. DGK-ζ is most abundant in brain and muscle. DGKs have structural motifs that play regulatory roles, and these motifs form the basis for dividing the DGKs into five subtypes. CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody



CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody CE, ISO9001 Approved Dgk-δ (S66) Polyclonal Antibody

 

Biological Products

PNEUTEC.IT, 2023