Pkc-Pan (T495) Polyclonal Antibody

Model NO.
BS1580
Host
Rabbit
Reactivity
Human, Mouse, Rat
Certification
CE, ISO9001
Transport Package
Refrigerated Transport
Specification
100ug/1mg
Trademark
Bioworld
Origin
China
HS Code
300219000
Production Capacity
3000 Vials
Reference Price
$ 222.75 - 247.50
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Product Description

Catalog No. BS1580
Product Name PKC-pan (T495) polyclonal antibody
Applications WB IHC IF
Alternative Name Protein kinase C alpha type; PKC-A; PKC-alpha; PRKCA; PKCA; PRKACA; Protein kinase C beta type; PKC-B; PKC-beta; PKCB; PRKCB1; PRKCB; Protein kinase C gamma type; PKC-gamma; PKCG; PRKCG; Protein kinase C delta type; Tyrosine-protein kinase PRKCD; nPKC-del
Swiss-Prot P17252    P05771    Q05655    Q02156    P05129    P24723    Q04759    Q05513   
Host Rabbit
Reactivity Human,Mouse,Rat
Application_all WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Product Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity PKC-pan (T495) polyclonal antibody detects endogenous levels of PKC α, β I, β II, γ, δ, ε, η, ζ and θ isoforms.
BiowMW ~75 to 88 kDa
Note For research use only, not for use in diagnostic procedure.
Immunogen Synthetic peptide, corresponding to amino acids 470-520 of Human PKC-pan.

  • Western blot (WB) analysis of PKC-pan (T495) polyclonal antibody at 1:500 dilution

  • Immunohistochemistry (IHC) analyzes of PKC-pan (T495) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Background

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms (δ, ε, ζ, η and θ). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC δ and ε are independent of Ca2+. Pkc-Pan (T495) Polyclonal Antibody Pkc-Pan (T495) Polyclonal Antibody



Pkc-Pan (T495) Polyclonal Antibody Pkc-Pan (T495) Polyclonal Antibody Pkc-Pan (T495) Polyclonal Antibody Pkc-Pan (T495) Polyclonal Antibody Pkc-Pan (T495) Polyclonal Antibody Pkc-Pan (T495) Polyclonal Antibody Pkc-Pan (T495) Polyclonal Antibody

 

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PNEUTEC.IT, 2023