(S)-(+)-1-Phenyl-1,2-ethanediol Chemical Properties |
Melting point | 64-67 °C(lit.) |
alpha | 66 º (c=1, chlor oform) |
Boiling point | 272-274 °C (755 mmHg) |
density | 1.0742 (rough estimate) |
refractive index | 40 ° (C=3, H2O) |
Fp | 320 °F |
storage temp. | Sealed in dry,Room Temperature |
pka | 13.61±0.20(Predicted) |
optical activity | [α]18/D +66°, c = 1 in chl oroform |
Water Solubility | soluble |
BRN | 3196197 |
CAS DataBase Reference | 25779-13-9(CAS DataBase Reference) |
Safety Information |
Hazard Codes | Xi,T |
Risk Statements | 23/24/25-36/37/38 |
Safety Statements | 24/25-45-36/37/39-26 |
WGK Germany | 3 |
Hazard Note | Irritant |
HS Code | 29062900 |
(S)-(+)-1-Phenyl-1,2-ethanediol Usage And Synthesis |
Chemical Properties | (S)-(+)-1-Phenyl-1,2-ethanediol is white to light yellow crystal powde |
Uses | (S)-(+)-1-Phenyl-1,2-ethanediol used as a chiral building block in organic synthesis, used in the preparation of chiral 2-amino-1-phenylethanols as pharmaceutical intermediates. |
Purification Methods | Purify the diol by recrystallisation from *C6H6/ligr oin and sublime it at 1-2mm. [Arpesella et al. Gazetta 85 1354 1955, Prelog et al. Helv Chim Acta 37 221 1954, Beilstein 6 IV 5939.] |