
| 4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Chemical Properties |
| Melting point | 97-99 °C(lit.) |
| Boiling point | 333.1±45.0 °C(Predicted) |
| density | 2.0589 (rough estimate) |
| refractive index | 1.5810 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in methan ol, dimethylsulfoxide, dimethylformamide and chlorofo rm. |
| pka | -5.65±0.50(Predicted) |
| form | Crystalline Powder |
| color | Yellow to light brown |
| Water Solubility | soluble |
| BRN | 614212 |
| CAS DataBase Reference | 10199-89-0(CAS DataBase Reference) |
| EPA Substance Registry System | 2,1,3-Benzoxadiazole, 4-chloro-7-nitro- (10199-89-0) |
| Safety Information |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-36/38 |
| Safety Statements | 36/37/39 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | DF8002400 |
| F | 10-21 |
| TSCA | Yes |
| HS Code | 29349990 |
| 4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Usage And Synthesis |
| Chemical Properties | yellow to light brown crystalline powder |
| Uses | 4-Chloro-7-nitrobenzofurazan is nonfluorescent until it reacts with primary or secondary amines to produce a fluorescent product. 4-Chloro-7-nitrobenzofurazan has been extensively used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines. |
| Uses | A fluorescent reagent |
| Definition | ChEBI: A benzoxadiazole that is 2,1,3-benzoxadiazole which is substituted at position 4 by chlorin e and at position 7 by a nitro group. |
| Purification Methods | Wash the solid with H2O, and it recrystallises from aqueous EtOH (1:1) as pale yellow needles. It sublimes in a vacuum [Gosh & Whitehouse Biochem J 108 155 1968, UV, NMR: Bolton et al. J Chem Soc 1004 1966]. |




