4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Chemical Properties |
Melting point | 97-99 °C(lit.) |
Boiling point | 333.1±45.0 °C(Predicted) |
density | 2.0589 (rough estimate) |
refractive index | 1.5810 (estimate) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Soluble in methan ol, dimethylsulfoxide, dimethylformamide and chlorofo rm. |
pka | -5.65±0.50(Predicted) |
form | Crystalline Powder |
color | Yellow to light brown |
Water Solubility | soluble |
BRN | 614212 |
CAS DataBase Reference | 10199-89-0(CAS DataBase Reference) |
EPA Substance Registry System | 2,1,3-Benzoxadiazole, 4-chloro-7-nitro- (10199-89-0) |
Safety Information |
Hazard Codes | Xn,Xi |
Risk Statements | 22-36/38 |
Safety Statements | 36/37/39 |
RIDADR | UN 2811 6.1/PG 3 |
WGK Germany | 3 |
RTECS | DF8002400 |
F | 10-21 |
TSCA | Yes |
HS Code | 29349990 |
4-Chloro-7-nitrobenzo-2-oxa-1,3-diazole Usage And Synthesis |
Chemical Properties | yellow to light brown crystalline powder |
Uses | 4-Chloro-7-nitrobenzofurazan is nonfluorescent until it reacts with primary or secondary amines to produce a fluorescent product. 4-Chloro-7-nitrobenzofurazan has been extensively used as a derivatizing reagent for chromatography analysis of amino acids and low molecular weight amines. |
Uses | A fluorescent reagent |
Definition | ChEBI: A benzoxadiazole that is 2,1,3-benzoxadiazole which is substituted at position 4 by chlorin e and at position 7 by a nitro group. |
Purification Methods | Wash the solid with H2O, and it recrystallises from aqueous EtOH (1:1) as pale yellow needles. It sublimes in a vacuum [Gosh & Whitehouse Biochem J 108 155 1968, UV, NMR: Bolton et al. J Chem Soc 1004 1966]. |