Rosuvastatina calcio CAS 147098-20-2 ad alta purezza anti-iperlipidemia

conservazione
conservare il luogo fresco e asciutto
mod
1 kg
requisiti di qualità
controllo di qualità rigoroso
grado
grado fagaceutico
risorsa
naturale
durata a magazzino
2 anni
metodo di prova
hplc
aspetto
polvere bianca
n. cas
147098-20-2
Pacchetto di Trasporto
Foil Bag
Specifiche
99%
Marchio
Xi′an Frazer Biotech Co., Ltd.
Origine
China
Capacità di Produzione
2000kg/Month
Prezzo di riferimento
$ 621.00 - 688.50
contattaci

Descrizione del Prodotto

High Purity Rosuvastatin Calcium CAS 147098-20-2 Anti-Hyperlipidemia

High Purity Rosuvastatin Calcium CAS 147098-20-2 Anti-Hyperlipidemia
High Purity Rosuvastatin Calcium CAS 147098-20-2 Anti-Hyperlipidemia
 
  Specification of Analysis

Tests

Specifications

Results

Appearance

A White to off-white powder

Complies

Specific Rotation

+17°~+21°

+20°

Identification

A. Meets the requirement

B. UV: λmax=243nm

C. IR: similar to Reference Substance

D.X-ray: similar to Reference Substance

Complies

Complies

Complies

Complies

Chloride

≤0.1%

Complies

Sulphate

≤0.1%

Complies

Enantiomer

≤0.15%

Undetected

Calcium

3.9%~4.3%

4.1%

Related substances

Diastereomer≤0.15%

0.06%

5-oxo-Rosucastatin≤0.15%

Undetected

Photo degradation 1≤0.15%

Undetected

Photo degradation 2≤0.15%

Undetected

Rosuvastatin lactone≤0.15%

Undetected

Rosuvastatin methyl ester≤0.15%

Undetected

Rosuvastatin isoamyl ester≤0.15%

Undetected

Any unknown impurity≤0.10%

0.05%

Total impurities≤0.75%

0.28%

Water

≤3.0%

2.1%

Isoamyl Bromide

≤37.5ppm

≤37.5ppm

Residual solvents

   

Isoamyl alcohol≤5000ppm Undetected

Undetected

DMF≤880ppm Undetected

Undetected

Assay

98.5%~102.0%( caculated on the anhydrous basis)

99.8%


Rosuvastatin Calcium is the calcium salt form of rosuvastatin, a statin with antilipidemic activity. Rosuvastatin selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol levels and increase in uptake of LDL cholesterol.

Function
1. Rosuvastatin is used to lower cholesterol and triglycerides (types of fat) in the blood and to slow the build-up of plaque
(fatty deposits) in your blood vessels.
2. Rosuvastatin is also used to lower the risk of stroke, heart attack, and other heart complications in certain people
with diabetes, coronary heart disease, or other risk factors.
3. Rosuvastatin is used in adults and children who are at least 10 years old.

Application
Rosuvastatin Calcium is an anti-hyperlipidemia (HMG-CoA) reductase inhibitor developed by AstraZeneca (UK) for the treatment of a variety of lipid disorders, including hypercholesterolemia, mixed lipid disorders and hypertriglyceridemia alone. High Purity Rosuvastatin Calcium CAS 147098-20-2 Anti-Hyperlipidemia
 

 

Mediatore Farmaceutico

PNEUTEC.IT, 2023