Hot Selling Levamisole Hydrochloride CAS 16595-80-5

Model NO.
16595-80-5
Transport Package
25kg
Specification
25kgs/drum, 1kg/foil bag
Trademark
Dujiang
Origin
Hubei, China
HS Code
29349990
Production Capacity
5000/Tons Per Year
Reference Price
$ 45.00 - 90.00
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Product Description

Product Description

Levamisole hydrochloride Basic information
Product Name: Levamisole hydrochloride
Synonyms: 1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(s)-imidazo(;1-b)thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,l-(-)-imidazo(;1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-Imidazo[2;citarinl;decaris;Imidazo[2,1-b]thiazole,2,3,5,6-tetrahydro-6-phenyl-,monohydrochloride,(S)-;kw-2-le-t;L-2,3,5,6-Tetrahydro-6-phenylimidazo-[2,1-6]-thiazole
CAS: 16595-80-5
MF: C11H13ClN2S
MW: 240.75
EINECS: 240-654-6
Levamisole hydrochloride Chemical Properties
Melting point  266-267 °C(lit.)
alpha  -128 º (c=5, H2O)
refractive index  -126 ° (C=1, H2O)
Fp  9ºC
storage temp.  2-8°C
solubility  Freely soluble in water, soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
form  Crystalline Powder
color  White to almost white
Water Solubility  210 g/L (20 ºC)
Levamisole hydrochloride Usage And Synthesis
Chemical Properties White to light yellow crystalline powder, odorless, bitter taste. Melting point 227-229ºC. Soluble in water, methanol, ethanol and glycerol, slightly soluble in chloroform and aether; insoluble in acetone. Stable under acidic conditions, but easy to decompose and fail under alkaline conditions.
Originator Solaskil,Specia,France,1971
Uses Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.
Uses Levamisole hydrochloride is an anthelmintic. The activity of levamisole is about twice as high as that of abscisicidal, and the toxicity and side effects are lower. Levamisole can cause muscle paralysis of roundworms and then excrete them in the feces. It is mainly used as an anti-worm and anti-hookworm.
Preparation Levamisole hydrochloride was prepared from racemic tetraimidazole by splitting, alkali analysis and acidification into salt.
Dibenzoyl-D-tartaric acid is boiled in water for 40min, hydrolyzed and neutralized with sodium hydroxide solution to pH 7.5, and then added to racemic tetraimidazole. The levamisole is precipitated by generating salt with bisbenzoyl-tartaric acid. After separation, add sodium hydroxide solution to PH=9 and decompose levamisole. Then dissolved in dilute hydrochloric acid solution, after decolorization by activated carbon, the filtrate was concentrated nearly dry, and crystallized by adding acetone and cooling to 0ºC. Filtered and dried to obtain levamisole hydrochloride.
Brand name Ergamisol (Janssen);Vermisol.
Therapeutic Function Antiinflammatory
Biochem/physiol Actions Shows both immunostimulant and immunosuppressant effects, depending on several controllable factors. Very effective in treatment of ascariasis (hookworm infestation). Useful in chemotherapy of colorectal cancers, possibly due to its stimulation of IL-1 production and direct activation of macrophages.
Pharmacokinetics Levamisole Hydrochloride is the hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunomodulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis.
Mode of action Levamisole is a cholinergic receptor agonist and elicits spastic muscle paralysis due to prolonged activation of the excitatory nicotinic acetylcholine receptors (nAChR) on nematode body wall muscle.
Toxicity evaluation Symptoms of levamisole toxicity mimic organophosphate toxicity (salivation, lacrimation, urination and defecation, hyperesthesia, seizures and irritability). There is no antidote for levamisole toxicity.
The World Health Organization reviewed hematological studies in animals and humans and derived acceptable daily intake for levamisole as 0.006 mg/kg body weight. This suggests a person can ingest 0.36 mg of levamisole/day over a lifetime without any appreciable risk.
levamisole

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Hot Selling Levamisole Hydrochloride CAS 16595-80-5

 

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Hot Selling Levamisole Hydrochloride CAS 16595-80-5

Packaging & Shipping

We use more specialized packaging for the different products you order.  We use aluminum foil bags to encrypt your package to prevent your product from being damaged in transit.  If you are concerned about safety, we can send your package using  "fake packaging"  to replace the name of the product.  Make sure you can receive your package safely.  We use different packaging methods for liquids and powders.  All in all you will be amazed by our shipping and packaging.


Hot Selling Levamisole Hydrochloride CAS 16595-80-5
Hot Selling Levamisole Hydrochloride CAS 16595-80-5
Hot Selling Levamisole Hydrochloride CAS 16595-80-5
SHIPPING

We guarantee that your package will pass 100% through the Mexico US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.
 
We have freight forwarders in these countries, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.
Hot Selling Levamisole Hydrochloride CAS 16595-80-5 PAYMENT
Hot Selling Levamisole Hydrochloride CAS 16595-80-5

 

Company Profile
Our company offers variety of products which can meet your multifarious demands. We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with. We can offer different quantities of custom synthetic chemicals on laboratory, factory and industrial scales. We can provide competitive prices for every customer and guarantee the quality of our products. We pay attention to the needs of each customer and build a good relationship with them. If you have any other questions for me. Please feel free to contact us. Our company provides a variety of products to meet your various needs. Since the establishment of the company, we adhere to the "quality first, customer first, credit oriented" business policy, always try our best to meet the potential needs of customers. With the development of economic globalization, our company is willing to cooperate sincerely with enterprises all over the world to achieve a win-win situation. We can supply different numbers of laboratory, factory and industrial scale custom synthetic chemicals. We can provide competitive prices for every customer and guarantee the quality of our products. We pay attention to the needs of each customer and build a good relationship with them. If you have any other questions for me. Please feel free to contact us. Our company offers variety of products which can meet your multifarious demands. We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with. We can offer different quantities of custom synthetic chemicals on laboratory, factory and industrial scales. We can provide competitive prices for every customer and guarantee the quality of our products. We pay attention to the needs of each customer and build a good relationship with them. If you have any other questions for me. Please feel free to contact us. Our company provides a variety of products to meet your various needs. Since the establishment of the company, we adhere to the "quality first, customer first, credit oriented" business policy, always try our best to meet the potential needs of customers. With the development of economic globalization, our company is willing to cooperate sincerely with enterprises all over the world to achieve a win-win situation. We can supply different numbers of laboratory, factory and industrial scale custom synthetic chemicals. We can provide competitive prices for every customer and guarantee the quality of our products. We pay attention to the needs of each customer and build a good relationship with them. If you have any other questions for me. Please feel free to contact us.
Hot Selling Levamisole Hydrochloride CAS 16595-80-5
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Hot Selling Levamisole Hydrochloride CAS 16595-80-5 Hot Selling Levamisole Hydrochloride CAS 16595-80-5
1) Most products  on stock , ship out within  1-3 days  !

2) Products are tested by QC department strictly before shipping !

3)  Make sure the part's safety with our strong shipping line  !

4) Customs pass and satisfied rate ≥99% !

5)  Responsible for all after-sale quality issues  !

 

FAQ

Q1. Can I have a sample order for your products?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.

Q2. What about the lead time?
A:Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity more than

Q3. Do you have any MOQ limit for order?
A: Low MOQ, 10-100g for sample checking is available

Q4. How do you ship the goods and how long does it take to arrive?
A: We usually ship by DHL, UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.

Q5. How to proceed an order for your products?
A: Firstly let us know your requirements or application. Secondly We quote according to your requirements or our suggestions.Thirdly   customer confirms the samples and places deposit for normal order.Fourthly We arrange the production.

Q6. Is it OK to print my logo on package?
A: Yes. Please inform us before our production and confirm the design firstly based on our sample.

Q7: Are you trading company or manufacturer?
A: We are chemical factory in China. So we can provide wholesale price



 

 

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