Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban

Model NO.
D-sung Argatroban
Shelf Life
2 Years
CAS No.
141396-28-3
Test Method
HPLC
Specific
COA
Melting Point
188-189°c
Density
1.47
MW
508.638
Mf
C23h36n6o5s
Grade
Pharmaceutical Grade
Color
White
Application
Antithrombotic
Assay
HPLC 99%
Product Name
Argatroban
Appearance
White Powder
Name
Argatroban Powder
Transport Package
Negotiable
Specification
99%
Trademark
D-sung
Origin
Shaanxi Xi′an
Production Capacity
500kg/Month
Reference Price
$ 288.00 - 450.00
Contact Us

Product Description

Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban
Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban
Product Description
Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban
Product Details
Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban
Product name Argatroban
Appearance White powder
CAS NO. 141396-28-3
MF C23H36N6O5S
MW 508.638
Argatroban is an anticoagulant that is a small molecule direct thrombin inhibitor.In 2000, argatroban was for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). In 2002, it was approved for use during percutaneous coronary interventions in patients who have HIT or are at risk for developing it. In 2012, it was approved by the MHRA in the UK for anticoagulation in patients with heparin-induced thrombocytopenia Type II  (HIT) who require parenteral antithrombotic therapy.
Argatroban is given intravenously and drug plasma concentrations reach steady state in 1-3 hours. Argatroban is metabolized in the liver and has a half-life of about 50 minutes. It is monitored by PTT. Because of its hepatic metabolism, it may be used in patients with renal dysfunction. (This is in contrast to lepirudin, a direct thrombin inhibitor that is primarily renally cleared).
Application&Function
Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban

Argatroban is used as an anticoagulant in individuals with thrombosis and heparin induced thrombocytopenia. Often these individuals allenges due to the falsely elevated prothrombin time and INR caused by argatroban. The combination of argatroban and warfari may raise the INR to greater than 5.0 without a significant increased risk of bleeding complications.One solution to this problem is to measure the chromogenic factor X level. A level < 40-45% typically indicates that the INR will be therapeutic (2-3) when the argatroban is discontinued.

Specification

Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban
Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban Antithrombotic CAS 141396-28-3 Argatroban Purity Argatroban Powder API Argatroban


 
 

 

Pharmaceutical Intermediate

PNEUTEC.IT, 2023