Factory Supply API Parecoxib Sodium CAS 198470-85-8

Model NO.
198470-85-8
Storage Condition
Store at Rt
Transport Package
Aluminium Foil Bag
Specification
kg
Trademark
FOUSI
Origin
China
Production Capacity
100000kg/Month
Reference Price
$ 9.00 - 90.00
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Product Description

 

Factory Supply API Parecoxib Sodium CAS 198470-85-8


Factory supply API PARECOXIB SODIUM CAS 198470-85-8
Product Description
 
CAS: 198470-85-8
MF: C19H17N2NaO4S
MW: 392.40405
EINECS: 813-689-5
Product picture

 

Factory Supply API Parecoxib Sodium CAS 198470-85-8

Product Parameters
Items Standards Results
Appearance White to off-white powder Complies
Identification By IR Complies
  By HPLC Complies
Water Content ≤1.00% 0.32%
Heavy Metals ≤20ppm Complies
Residue on Ignition ≤0.20% 0.08%
Residual Solvent Eth yl Acetate: ≤5000ppm Complies
  Ethanol: ≤5000ppm Complies
Related Substances Any individual impurity: ≤0.10% 0.05%
  Total Impurities: ≤1.00% 0.40%
Assay
(HPLC basis on drying) 		98.0%~102.0% 99.70%
Reference Standard In-house Standard
Conclusion The product complied  to  In-house standard.
Storage Preserve in tight,light-resistant containers in a cool place


What is Parecoxib ?
Parecoxib is a water soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx). As it is injectable, it can be used perioperatively when patients are unable to take oral medications. Parecoxib 99%/198470-84-7.

FUNCTION AND APPLICATION
It is approved through much of Europe for short term perioperative pain control much in the same way ketorolac(Toradol) is used in the United Parecoxib 99%/198470-84-7 States. However, unlike ketorolac, parecoxib has no effect on platelet function and therefore does not promote bleeding during or after surgery.

In addition, ketorolac has a much higher gastrointestinal toxicity profile compared to most other nonsteroidal antiinflammatory drugs (NSAIDs) including ibuprofen and naprosyn. However, in the United States ketorolac is the only injectable NSAID, although it is banned in many European countries due to concerns about surgical bleeding and stomach ulcers after surgery.


 
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Factory Supply API Parecoxib Sodium CAS 198470-85-8

Company Profile

 

Factory Supply API Parecoxib Sodium CAS 198470-85-8 Factory Supply API Parecoxib Sodium CAS 198470-85-8 Factory Supply API Parecoxib Sodium CAS 198470-85-8
 
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Pharmaceutical Intermediate

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