Product Description
Product Name
|
Veliparib
|
Appearance
|
White Powder
|
Specification
|
≥99%
|
MOQ
|
10g
|
MF
|
C13H16N4O
|
MW
|
244.292
|
CAS
|
912444-00-9
|
Shelf Life
|
2 Years
|
Veliparib
is a poly(ADP-ribose) polymerase (PARP) -1 and -2 inhibitor with chemosensitizing . With no antiproliferative effects as a single agent at therapeutic concentrations, ABT-888 inhibits PARPs, thereby inhibiting DNA repair and potentiating the cytotoxicity of DNA-damaging agents.
Certifications
Application
ABT-888 effectively inhibits PARP, with Ki values of 5.2 and 2.9 nM when acting on PARP-1 and PARP-2, respectively;
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