Product Name | Supply Beat Selling CAS 150399-23-8 Powder Pemetrexed Disodium |
Appearance | White powder |
Molecular formula | C20h22n5nao6 |
Molecular weight | 451.41 |
Keywords | Powder Pemetrexed Disodium ,Price Pemetrexed Disodium; Pure Pemetrexed Disodium |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
What is Pemetrexed Disodium
Pemetrexed disodium is a kind of multi-target anti folate preparation with group as its core. It is a dual inhibitor of nucleotide synthase / dihydrofolate reductase. It can inhibit cell replication by destroying the normal folate dependent metabolism process in cells, and can simultaneously block three different enzyme targets that are crucial to the survival of cancer cells, thus inhibiting tumor growth.
Function of
Pemetrexed Disodium
1. Pemetrexed Disodium is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively
2.
Pemetrexed Disodium is a m
ultitargeted antifolate; inhibits thymidylate synthase as well as other folate dependent enzymes. Antineoplastic.