Manufacturer Supply High Quality Bifendate / BifendatatuM API / CAS 73536-69-3
Product Name
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Manufacturer Supply High Quality Bifendate / BifendatatuM API / CAS 73536-69-3
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CAS NO.
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73536-69-3
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Appearance
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White Powder
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Purity
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99%
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Melting Point
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179-181 °C
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Boiling Point
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606.9±55.0 °C
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Density
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1.390±0.06 g/cm3
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Storage
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2-8°C(protect from light)
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Application
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Pharmaceutical raw materials; The raw material; Intermediates
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Usage
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Bifendate is commonly used in the pharmaceutical industry.
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Bifendate is a synthetic intermediate of Schisandrin C and also an anti-HBV drug used in Chinese medicine for the treatment of chronic hepatitis B. Following the intake of Bifendate in rats, the drug was observed to improve liver function by increasing the detoxification process, reducing pathological lesions, and accelerating hepatocyte regeneration. Bifendate can also function as a membrane-stabilizing agent to protect the cell from damage. After treatment with Bifendate, the protein metabolic processes of hepatitis patients were improved, with increased serum albumin levels and decreased globulin levels. Bifendate is a potent inducer of cytochrome proteins (CYPs) and can result in clinically significant interactions. It has been proposed that the increased detoxification capability of Bifendate originates from an increase in the level of P450. Bifendate may function as a protecting agent to prevent drug-induced liver dysfunction by increasing the activity of CYP450.
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