Specification | 4% | Usage | Anthelmintic / Antibiotic |
Raw Material | Ivermectin | Species | Cattle, sheep, swine, camels,chicken |
Dosage Form | Injection | Sample | Yes |
Packing |
100ml/vial/box*80boxes/carton
50ml/vial/box*120boxes/carton 30ml/vial/box*200boxes/carton 20ml/vial/box*30boxes/carton 10ml/vial/box*500boxes/carton |
Delivery Time | 15-20days |
MOQ | 500L | Payment Term | T/T, D/P, D/A, L/C |
GMP | Yes | ISO9001 | Yes |
FDA | Yes | COS | Yes |
Ivermectin injection
Indications
Ivermectin injection is indicated for the effective treatment and control of parasites.
Pharmacology and Mechanism of Action
Antiparasitic:
Avermectins (Ivermectin-like
medicine
s) and milbemycins (milbemycin and moxidectin) are macrocyclic lactiones and share similarities, including mechanism of action. These
product
s are neurotoxic to parasites by protentiating glutamate-gated chloride ion channels in parasites. Paralysis and death of the parasite are caused by increased permeability to chloride ions and hyperpolarization of nerve cells. These
products also potentiate other chloride channesl, indlucing ones gated by GABA.
Mammals ordinarily are not affected because they lack glutamate-gated chloride channels, and there is a lower affinity for other mammalian chloride channels. Because these products ordinarily do not penetrate the blood-brain barrier, GABA-gated channels in the CNS of mammals are not affected. Ivermectin is active against intestinal parasites, mites, bots, heartworm microfilaria, and developing larvae.
Ivermectin can also produce heartworm adulticide effects when administered long-term. Ivermectin has no effect on trematode or cestode parasites.
Administration and Dosage:
Ivermectin should be administrated only by subcutaneous injection beneath the loose skin behind the shoulder.
1ml \ 50 kg
Withdrawal:
Cattle, Sheep must not be treated within 35Days of slaughter for human consumption.
Storage:
Protect from direct sunlight and store below 30°C.
Prodution workshop: