USP Raw Powder Montelukast Sodium with CAS 151767-02-1

Model NO.
Alpha-Montelukast sodium
Keywords
Montelukast Sodium
Appearance
White Powder
Form
Powder
M.F.
C35h35clnnao3s
Delivery Time
7-10 Days
Type
API
Shelf Life
24 Month
Color
White
Storage
Cool Dry Place
Grade Standard
USP/Bp
CAS
151767-02-1
Other Names
Montelukast Sodium
MOQ
1kg
Sample
Available
Product Name
Montelukast Sodium
Transport Package
1kg/Aluminium Foil Bag, 25kg/Drum with Plastic Bag
Specification
99%
Trademark
Alpha
Origin
Shaanxi, China
Production Capacity
5000 Kilogram/Kilograms Per Month
Reference Price
$ 405.00 - 495.00
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Product Description

USP Raw Powder Montelukast Sodium with CAS 151767-02-1
 
USP Raw Powder Montelukast Sodium with CAS 151767-02-1
Product Name USP Raw Powder Montelukast Sodium with CAS 151767-02-1
Appearance white powder
CAS 151767-02-1
OEM/ODM Yes
Keywords Montelukast Sodium
Shelf Life 24 months when properly stored
Storage Keep in a cool, dry, dark location
 
USP Raw Powder Montelukast Sodium with CAS 151767-02-1 What is   Montelukast Sodium ?

Montelukast Sodium is a potent, selective, anti-inflammatory CysLT1 receptor antagonist (IC50 < 5nM) with no appreciable affecton the CysLT2 receptor. In rat colitis Montelukast Sodium has demonstrated the ability to increase PGE2 (Prostaglandin E2 - sc-201225) production and lower COX-2 expression. Inhibition is competitive with respect to leukotrienes - particularly LTD4, a biologically active mediator that plays an important role in the control of several biochemical pathways involving pulmonary and immune system function.Because of its method of operation, it is not useful for the treatment of acute asthma attacks. Again because of its very specific mechanism of action, it does not interact with other asthma medications such as theophylline.Another leukotriene receptor antagonist is zafirlukast (Accolate), taken twice daily. Zileuton (Zyflo), an asthma drug taken four times per day, blocks leukotriene synthesis by inhibiting 5-lipoxygenase, an enzyme of the eicosanoid synthesis pathway.
 
 
USP Raw Powder Montelukast Sodium with CAS 151767-02-1
Function of   Montelukast Sodium
Montelukastis a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies.Montelukast comes as a tablet, a chewable tablet, flash tablet and granules to take by mouth.Montelukast is usually taken once a day with or without food.Montelukast is a CysLT1 antagonist; it blocks the action of leukotriene D4 (and secondary ligands LTC4 and LTE4) on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene and results in less inflammation.


Application of   Montelukast Sodium

Montelukast is used for a number of conditions including asthma, exercise induced bronchospasm, allergic rhinitis, primary dysmenorrhoea and urticaria. It is mainly used as a complementary therapy in adults in addition to inhaled corticosteroids, if they alone do not bring the desired effect. It is also used to prevent allergic reactions and asthma flare-ups during the administration of intravenous immunoglobulin.
 
USP Raw Powder Montelukast Sodium with CAS 151767-02-1
 
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USP Raw Powder Montelukast Sodium with CAS 151767-02-1

Focus on the development and production of Active Pharmaceutical Ingredients (APIs)

 

Xi'an Alpha Biotech Co.,Ltd  was founded in 1962 and is located in Xi'an City, Shannxxi province, covering an area of 13,000 m2. Adhering to the quality policy of " Customer Satisfaction, Wisdom Combination, Quality Improvement, and Striving for Excellence" for more than 50 years, we has obtained cGMP certificates from the US FDA and TFDA. We focus on the development and production of Active Pharmaceutical Ingredients (APIs). The products are sold to dozens of countries such as the United States, Indonisia, Europe, Canada, Italy, Australia ... etc.
USP Raw Powder Montelukast Sodium with CAS 151767-02-1

USP Raw Powder Montelukast Sodium with CAS 151767-02-1 USP Raw Powder Montelukast Sodium with CAS 151767-02-1
USP Raw Powder Montelukast Sodium with CAS 151767-02-1 USP Raw Powder Montelukast Sodium with CAS 151767-02-1
USP Raw Powder Montelukast Sodium with CAS 151767-02-1







 

 

Pharmaceutical Intermediate

PNEUTEC.IT, 2023