CE، UMP-CMP Kinase (E36) معتمد من قبل ISO9001، الجسم المضاد متعدد الأضلاع

نموذج رقم.
BS1975
المضيف
أرنب/ماوس
إعادة النشاط
الإنسان والفأر والفأر
شهادة
CE، ISO9001
حزمة النقل
Refrigerated Transport
تخصيص
100ug/1mg
العلامة التجارية
Bioworld
الأصل
China
رمز النظام المنسق
300219000
القدرة الإنتاجية
3000 Vials
السعر المرجعي
$ 222.75 - 247.50
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وصف المنتجات

Catalog No. BS1975
Product Name UMP-CMP Kinase (E36) polyclonal antibody
Applications WB IHC IP
Alternative Name UMP-CMP kinase; Deoxycytidylate kinase; dCMP kinase; Nucleoside-diphosphate kinase; Uridine monophosphate/cytidine monophosphate kinase; UMP/CMP kinase; UMP/CMPK; CMPK1; CMK; CMPK; UCK; UMK; UMPK
Swiss-Prot P30085
Host Rabbit
Reactivity Human,Mouse,Rat
Application_all WB: 1:500~1:1000 IHC: 1:50~1:200 IP: 1:10~1:100
Product Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity UMP-CMP Kinase (E36) polyclonal antibody detects endogenous levels of UMP-CMP Kinase protein.
BiowMW ~ 26 kDa
Note For research use only, not for use in diagnostic procedure.
Immunogen Synthetic peptide, corresponding to the N-terminal of Human UMP-CMP Kinase.

  • Western blot (WB) analysis of UMP-CMP Kinase (E36) pAb at 1:1000 dilution Lane1:Hela whole cell lysate(40ug) Lane2:H9C2 whole cell lysate(40ug) Lane3:MEF whole cell lysate(40ug) Lane4:A549 whole cell lysate(40ug) Lane5:HEK293T whole cell lysate(40ug)

  • Immunohistochemistry (IHC) analyzes of UMP-CMP Kinase (E36) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

  • Immunoprecipitation of HEK293T cell lysate using UMP-CMP Kinase (E36) pAb (Sepharose Bead Conjugate) #BD0048(lane 2 and lane 3) and Nonspecific IgG Control (Sepharose Bead Conjugate) #BD0048 (lane 4 and lane 5) .Lane 1 is 30% input. The western blot was

Background

Nucleoside monophosphate kinases are required for pharmacological activation of therapeutic nucleosides and nucleotide analogs. CMPK (Cytidine monophosphate kinase), also known as UMP-CMP kinase and Deoxycytidylate kinase, is a 196 amino acid protein that catalyzes the phosphoryl transfer from ATP to UMP, CMP and dCMP. This enzymatic reaction leads to the formation of ADP and the corresponding nucleoside diphosphate, which are required for cellular nucleic acid synthesis. Primarily localized to the cytoplasm, CMPK also plays an important role in the activation of pyrimidine analogs, which is clinically useful anti-cancer and anti-viral drugs. CMP is the best substrate for CMPK, followed by UMP and dCMP. CE, ISO9001 Approved Ump-CMP Kinase (E36) Polyclonal Antibody CE, ISO9001 Approved Ump-CMP Kinase (E36) Polyclonal Antibody



CE, ISO9001 Approved Ump-CMP Kinase (E36) Polyclonal Antibody CE, ISO9001 Approved Ump-CMP Kinase (E36) Polyclonal Antibody CE, ISO9001 Approved Ump-CMP Kinase (E36) Polyclonal Antibody CE, ISO9001 Approved Ump-CMP Kinase (E36) Polyclonal Antibody CE, ISO9001 Approved Ump-CMP Kinase (E36) Polyclonal Antibody CE, ISO9001 Approved Ump-CMP Kinase (E36) Polyclonal Antibody CE, ISO9001 Approved Ump-CMP Kinase (E36) Polyclonal Antibody

 

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