HPLC NMR-getestete Nootropics Supplements 7 8-Dihydroxyflavone 7 8-DHF Powder CAS 38183 -03-8 Lagerversorgung

Yinherb Lab CAS 38183-03-8 7,8-Dihydroxyflavone Hydrate Raw Powder 99% Purity 
English name: 7,8-Dihydroxyflavone Hydrate
CAS number: 38183-03-8
Molecular formula: C17H22N2O4
Molecular weight: 254.24
Melting point 23-25 °C
Boiling point 128-130 °C (14 mmHg)
Density 1.00 g/mL at 20 °C
Refractive index n20/D 1.479(lit.)
Flash point >230°F
Storage conditions 2-8°C
Solubility H2O: 1 M at 20 °C, clear, colorless
Form: Liquid After Melting
Acidity coefficient (pKa):10.53±0.19 (Predicted)
Specific gravity: 0.925
PH value: 12.0-13.5 (25ºC, 1M in H2O)
Water solubility: Miscible with water, ethanol and ether.
Place of Origin: China Yinherb-Lab
Packing: As per client's requirements
Minimum Order Quantity: 1kg
Storage: Store in cool & dry place, Keep away from strong light and heat for 2 years


What is 7,8-Dihydroxyflavone Hydrate?
7 8-Dihydroxyflavone (7,8-DHF) is a naturally occurring flavone found in Godmania aesculifolia, Tridax procumbens, and primula tree leaves. It has been found to act as a potent and selective small-molecule agonist of the tropomyosin receptor kinase B (TrkB) (Kd ≈ 320 nM), the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF).

7,8-DHF is both orally bioavailable and able to penetrate the blood-brain barrier. A prodrug of 7,8-DHF with greatly improved potency and pharmacokinetics, R7, is under development for the treatment of Alzheimer's disease.

7,8-Dihydroxyflavone Hydrate  Benefits
1. 7,8-dihydroxyflavone has demonstrated remarkable therapeutic efficacy in animal models of a variety of central nervous system disorders, including depression, Alzheimer's disease, cognitive deficits in schizophrenia, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, cerebral ischemia, fragile X syndrome, and Rett syndrome.

2. 7,8-dihydroxyflavone also shows efficacy in animal models of age-associated cognitive impairment and enhances memory consolidation and emotional learning in healthy rodents.

3. 7,8-dihydroxyflavone possesses powerful antioxidant activity independent of its actions on the TrkB receptor, and protects against
glutamate-induced excitotoxicity, 6-hydroxydopamine-induced dopaminergic neurotoxicity, and oxidative stress-induced genotoxicity.





FAQ
Q1: Can i get some samples 
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
 
Q2: How to start orders or make payments 
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Q3: How to confirm the Product Quality before placing orders 
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Q4:What's your MOQ 
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
 
Q5: How about delivery leadtime 
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
 
Q6:Is there a discount 
A:Different quantity has different discount.
 
Q7: How do you treat quality complaint 
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.