Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib

Model NO.
TY-02AL
Colour
White
Assay
99%
Shelf
2 Years
Place
China
Package
Foil Bag
Transport Package
25kg/Drum 5g, 100g, 500g, 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
Contact Us

Product Description

Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib
Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib

Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib
 
Product name Niraparib
CAS 1038915-60-4
Appearance white powder
Assay 99%
Storage Cool and Protect from light


Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib

Niraparib
Product Name Niraparib

CAS 1038915-60-4

MF C19H20N4O

MW 320.39

EINECS

MOL File1038915-60-4.mol    Chemical Properties

Boiling point 463.6±45.0 °C(Predicted)
Density  1.34
storage temp.  2-8°C(protect from light)
pka 15.36±0.30(Predicted)

Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib
Usage And Synthesis
Uses

Niraparib is a novel oral poly(ADP-ribose)polymerase (PARP) inhibitor efficacious in BRCA-1 and -2 mutant tumors.

Description

(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide is also known as MK-4827(Niraparib) tosylate is a selective inhibitor of PARP1/PARP2 (The poly(ADP-ribose) polymerase) with great activity in cancer cells with mutant BRCA-1 and BRCA-2. It has been recently approved by FDA for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in complete or partial response to platinum-based chemotherapy. In vitro studies have shown that niraparib-induced cytotoxicity may involve inhibition of PARP enzymatic activity and increased formation of PARP-DNA complexes resulting in DNA damage, apoptosis and cell death.

GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.

Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.

Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.

Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib Manufacturer Supply High Quality CAS 1038915-60-4 Niraparib

 

Organic Intermediate

PNEUTEC.IT, 2023