Introduction:

Alpha GPC 28319-77-9 rapidly delivers choline to the brain across the blood-brain barrier and is a biosynthetic precursor of the acetylcholine neurotransmitter.Alpha GPC is derived from highly purified soy lecithin by companies like Lipoid, VAV Life Sciences, Chemi SPA etc.

Studies have investigated its efficacy for cognitive disorders including stroke and Alzheimer's Disease. An Italian multicentre clinical trial on 2,044 patients suffering from recent stroke were supplied alpha-GPC in doses of 1,000 mg/day for 28 days and 400 mg three times per day for the five ensuing months. The trial confirmed the therapeutic role of alpha-GPC on the cognitive recovery of patients based on four measurement scales, three of which reached statistical significance.

Commonly used doses are 300-1,200 mg daily. 

Function:

1. increases in endogenous human Growth  secretion by the anterior pituitary in conjunction with Growth  Releasing Hormone (GHRH); that is, both Alpha-G.P.C. and GHRH act concertedly to stimulate the release , naturally;2. stimulation of the enzymatic synthesis of phosphatidylcholine (PC) in nerves, muscle cells and all cell membranes, counteracting the age-related decrease in phospholipid (PC) biosynthesis; thus, Alpha-GPC contributes directly to improved mental focus and stimulation of cognitive function;3. acts as a precursor of acetylcholine (ACh); thus, Alpha-GPC activates cholinergic transmission which permits the development of more strength from work-outs and training programs, plus reducing levels of somatostatin in the hypothalamic-pituitary axis;4. elevations in blood and tissue levels of the essential nutrient, choline, which supports improved lipotrophic functions (methyl group transferases) in the liver, and acts synergistically with S-adenosyl-L-methionine (SAM or SAMe) and folic acid, vitamin B12 and vitamin B6 to facilitate methyl group transfers in the brain and liver;5. produces improved balanced and coordination when combined with 'skill set' practice and training as a result of normalized nerve transmission in the brain, and in cardiac, skeletal and smooth muscles.

Application:
 

The main benefit to Alpha GPC is its noticeable nootropic qualities. It is used as a prescription medication and has merit in treating many mental deficiencies. Alpha GPC has qualities of treating overall general mental health including: learning and memory, thinking skills and mood.

Specifications: