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Pharmaceutical Intermediate
Duloxetine Hydrochloride CAS 136434 -34-9 Duloxetine HCl
Model NO.
TY-02ALI
Einecs
616-396-9
Shelf
2 Years
Assay
99%
Appearance
White Powder
CAS
136434-34-9
Transport Package
25kg/Drum 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
$ 2.70 - 4.50
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Description
Product Description
Product name
Duloxetine hydrochloride
CAS
136434-34-9
Appearance
white powder
Assay
99%
Storage
Cool and Protect from light
Product Name:Duloxetine hydrochloride
CAS:136434-34-9
MF:C18H20ClNOS
MW:333.88
EINECS:603-962-5
Mol File:136434-34-9.mol
Melting point:118-122°C
Flash point:9ºC
storage temp. -20°C Freezer
solubility H2O: soluble5mg/mL (clear solution, warmed)
pkapKa in DMF-water (66:34): 9.6(at 25ºC)
form powder
color white to beige
optical activity[α]/D +116 to +125°, c = 1 in methanoles
Duloxetine hydrochloride is the salt form of antidepressant drug duloxetine. It was successfully developed by Eli Lilly Company. Its pharmacological effect is the same as duloxetine. Duloxetine hydrochloride is a new kind of selective dual inhibitor of 5 hydroxy trptamine (5-HT) and norepinephrine reuptake, and thus having antidepressant effect, while also having inhibitory effect on the central pain. Its pharmacological characteristic is being able to inhibit neuronal pre-synaptic membrane's reuptake on 5-hydroxy trptamine and norepinephrine but instead have a low inhibitory effect on the reuptake of dopamine. Duloxetine hydrochloride is indicated for depression and it is effective in treating both endogenous and non-endogenous depression as well as the feeling of pain associated with depression. It has a therapeutic dose of 60mg/d~120mg/d with a good security and fewer adverse reactions with common adverse reactions such as nausea, dry mouth, constipation, poor appetite, fatigue, sleepiness, and increased sweating. Another indication is the pain caused by diabetic neuropathy.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.
Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.
Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.
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