Pharmaceutical Intermediate Antidepressants API Powder CAS 136434 -34-9 Duloxetine Hydrochloride

Shipping Area
Worldwide/All Countries
Assay
99%
Service
Good Service
Delivery Method
FedEx/DHL/Special Line
CAS
136434-34-9
Storage
Keep in Cool and Dry Place
Test Method
HPLC
Delivery
Express 5-7 Days Arrive
Shelf Life
2 Years
Appearance
White Powder
Transport Package
Foil Bag
Specification
99%
Trademark
Xi′an Frazer Biotech Co., Ltd.
Origin
China
Production Capacity
200kg Per Month
Reference Price
$ 3,195.00 - 3,285.00
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Product Description

Pharmaceutical Intermediate Antidepressants API Powder CAS 136434-34-9 Duloxetine Hydrochloride
Pharmaceutical Intermediate Antidepressants API Powder CAS 136434-34-9 Duloxetine Hydrochloride
Pharmaceutical Intermediate Antidepressants API Powder CAS 136434-34-9 Duloxetine Hydrochloride

Specification of Analysis

ITEMSPECIFICATIONRESULTS          
ColorWhite to off white color powder   Complies
Chloride testShould be positive   Complies
Specification rotation115 °~ +125°   +120.52°
Water content by KFR ≤1.0% w/w   0.13%w/w
Sulphated ash≤0.1% w/w   0.06%w/w
Heavy Metals≤10ppm    5ppm
Relative Substances  
Thiop hene amine impurity≤0.15%    N.D.
Naphthol impurity≤0.15%    N.D.
Max single impurity≤0.1%    0.02%
Total impurity≤1.0%    0.03%
Assay(HPLC)98.0% ~ 102.0%     101%


What is Duloxetine hydrochloride ?

Duloxetine hydrochloride is the salt form of antidepressant drug duloxetine.Its pharmacological effect is the same as duloxetine. It  is a new kind of selective dual inhibitor of 5 hydroxy trptamine (5-HT) and norepinephrine reuptake, and thus having antidepressant effect, while also having inhibitory effect on the central pain.

Function

1. Duloxetine hydrochloride can inhibit neuron to 5 a serotonin and norepinephrine reuptake, thus raising the two central neurotransmitter concentrations in the brain and spinal cord.
2. Duloxetine hydrochloride can be used to treat some mood disorders such as depression and anxiety symptoms and alleviate central pain such as diabetic peripheral neuropathic pain and women fibromyalgia, etc.
3.Duloxetine hydrochloride can also be applied to the urethra serotonin and norepinephrine receptors, resulting in increased urethral sphincter nervous tension and contraction ability, so the stress urinary incontinence disease treatment is effective for women.

Application

1) In the regulation of emotion and pain sensitivity plays an important role.
2) Duloxetine hydrochloride Can be used to treat some mood disorders such as depression and anxiety, and
reduce central pain such as diabetic peripheral neuropathic pain and women such as fibromyalgia.
3) For women with stress urinary incontinence disease treatment is effective.

Pharmaceutical Intermediate Antidepressants API Powder CAS 136434-34-9 Duloxetine Hydrochloride

 

 
 
 
 
 
 

 

Pharmaceutical Intermediate

PNEUTEC.IT, 2023