Pharmaceutical Intermediate Sugammadex sodium Powder CAS 343306-79-6 OEM
Description
Sugammadex Sodium is the sodium salt form of the biologically inert, selective relaxant binding agent (SRBA) sugammadex, a modified, anionic gamma cyclodextrin derivative containing a hydrophilic exterior and a hydrophobic core, with neuromuscular blocking drug (NMBD) reversal activity. Upon administration, the negatively charged carboxyl-thio-ether groups of sugammadex selectively and reversibly bind to the positively charged quaternary nitrogen of a steroidal NMBD, which was administered at an earlier time for anesthetic purposes. The encapsulation of the NMBD by sugammadexblocks its ability to bind to nicotinic receptors in the neuromuscular junction and thereby reverses the NMBD-induced neuromuscular blockade. Sugammadex binds rocuronium, vecuronium, and to a lesser extent pancuronium.
Quick Details
Chemical Name | Sugammadex |
---|---|
Synonyms | Org 25969;Sugammadex sodium;Bridion; |
CAS No. | 343306-79-6 |
Molecular Formula | C72H104Na8O48S8 |
Molecular Weight | 2178.01000 |
PSA | 994.80000 |
LogP | -18.35920 |
Usage:
Essential information of Sugammadex sodium CAS 343306-79-6
A selective relaxing antagonist that can be used to reverse neuromuscular blockers and is useful for antagonizing rocuronium or vecuronium-induced neuromuscular blockade
More information of Sugammadex sodium CAS 343306-79-6
Storage:It should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.
Application of Sugammadex sodium CAS 343306-79-6
It can be used to reverse neuromuscular blockers and can be useful for antagonizing rocuronium or vecuronium-induced neuromuscular blockade.
Packing:
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Pharmaceutical Intermediate Sugammadex sodium Powder CAS 343306-79-6 OEM