Pharmaceutical Intermediates Darunavir CAS 206361-99-1 Antibiotics

Model NO.
LDKJ01-47
Colour
White
Form
Powder
Shelf Life
2 Years
Color
White
Mf
Darunavir
CAS
206361-99-1
Transport Package
25kg Carton Drum (32cm*58cm)or 1kg Foil Bag (10cm*
Specification
1kg/bag
Trademark
Lingding
Origin
Hebei, China
Production Capacity
8000kilogram/Per Month
Reference Price
$ 90.00 - 135.00
Contact Us

Product Description

Pharmaceutical Intermediates Darunavir CAS 206361-99-1 AntibioticsHigh Purity Antiviral Darunavir CAS 206361-99-1 with Best Quality
 

Product Description

Product Name:Darunavir
CAS:206361-99-1
MF:C27H37N3O7S
MW:547.66
EINECS:606-590-1


Darunavir is the latest weapon in the arsenal of agents to combat human immunodeficiency virus type 1(HIV-1). As an HIV-1 protease inhibitor, its mechanism of action involves blocking the cleavage of the gag and gag-pol polyproteins into functional proteins essential for the production of infectious progeny virus; the result is the production of immature, noninfectious viral particles. Compared to predecessor HIV protease inhibitors, darunavir retains activity against resistant stains, a critical factor with the continual emergence of multidrug- resistant (MDR) mutants. Despite experiencing a 13-fold reduction in binding to MDR HIV-1 protease, this binding is 1.5 orders of magnitude tighter than the first-generation protease inhibitors. Furthermore, darunavir exhibits less than a 10-fold decrease in susceptibility in cell culture against 90% of 3309 clinical isolates resistant to amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir, saquinavir, and tipranavir. In contrast, darunavir-resistant viruses display limited susceptibility to only tipranavir, suggesting limited cross-resistance between these two protease inhibitors. To avoid the issues of the peptide-based protease inhibitors, darunavir has evolved from a structure-based design effort to minimize peptidic features and reduce molecular weight and complexity.
 

Pharmaceutical Intermediates Darunavir CAS 206361-99-1 Antibiotics

 

Pharmaceutical Intermediates Darunavir CAS 206361-99-1 Antibiotics

 

Pharmaceutical Intermediates Darunavir CAS 206361-99-1 Antibiotics

 

Packaging & Shipping

Packaging Details

25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients

Port:TIANJIN

 

Pharmaceutical Intermediates Darunavir CAS 206361-99-1 Antibiotics

 

 

 

 

Pharmaceutical Intermediates Darunavir CAS 206361-99-1 Antibiotics

 

 

Pharmaceutical Intermediates Darunavir CAS 206361-99-1 Antibiotics
 
 

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Company Profile

Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.
 

Pharmaceutical Intermediates Darunavir CAS 206361-99-1 Antibiotics

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Pharmaceutical Intermediates Darunavir CAS 206361-99-1 Antibiotics

 

 

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