Organic Intermediate Antitumor Imatinib Powder CAS 152459-95-5 Imatinib Powder High Purity
Product Name
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Organic Intermediate Antitumor Imatinib Powder CAS 152459-95-5 Imatinib Powder High Purity
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Shape
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White powder
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Molecular formula
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C29H31N7O
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Keywords
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Imatinib;Imatinib Powder;Imatinib CAS 152459-95-5
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Shelf Life
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24 months when properly stored
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Storage
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Keep in a cool, dry, dark location
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What is Imatinib ?
Imatinib Mesylate is a specific tyrosine kinase (abl, c-kit, and PDGFR) inhibitor and is reported to sensitize cells to radio- or chemo-therapy. When tested with Y-79 and WERI-RB-1 Rb cell lines, imatinib mesylate treatment decreased the cell proliferation and invasion with the concentration of 10 μM . In osteoblast cells, administration of imatinib mesylate decreased osteoclast development via stimulating differentiation, inhibiting proliferation and survival .
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Function of Imatinib mesylate
A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)
Application of Imatinib mesylate
Cells were stimulated with allogeneic mature DCs or PHA in the presence of imatinib mesylate. The drug inhibited T-cell proliferation as a function of concentration. The effects were significant at 0.5 μM imatinib mesylate for the cells stimulated by DCs and at 1.0 μM imatinib mesylate for the cells stimulated with PHA. The IC50 values for imatinib mesylate-inhibited T-cell proliferation stimulated by DCs and PHA were 3.9 μM and 2.9 μM, respectively..
Pharmaceutical Intermediate Antitumor Raw Material CAS 152459-95-5 Imatinib Powder
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Active Pharmaceutical Ingredients Raw Material; Pharmaceutical Active Ingredients, Pharmaceutical Intermediates, API Raw Material Supplier
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Q: What's your MOQ ?
A:
For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q:
Is there a discount ?
A:
Yes, for larger quantity, we always support with better price.
Q:
How to confirm the Product Quality before placing orders ?
A:
You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q:
How to start orders or make payments ?
A:
You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q:
How do you treat quality complaint ?
A:
First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Pharmaceutical Intermediate Antitumor Raw Material CAS 152459-95-5 Imatinib Powder