Free Sample Nicotinamide Riboside Chloride Nrcl CAS 23111-00-4 Health Supplement

Application

Nicotinamide riboside is involved in nicotinate and nicotinamide metabolism. Nicotinamide riboside was originally identified as a nutrient in milk and later discovered to be a NAD(+) precursor.
Nicotinamide riboside (NR) is a naturally occurring vitamin B-3 present in the human diet that acts as an NAD+ precursor and is suggested to improve mitochondrial function and in sulin sensitivity. NR acts via activation of the NAD+-dependent sirtuin enzyme family, thereby regulating oxidative metabolism. In vitro experiments of NR supplementation have shown its successful NAD+-restoring capability and subsequent increased oxidative gene expression in skeletal muscle cells. Results from in vivo mouse models have shown improvements in in sulin sensitivity and oxidative energy metabolism, including enhanced metabolic flexibility, increased aerobic exercise capacity, and indications of improved mitochondrial biogenesis.

Health Benefits

• Amplifies muscle endurance : NMN supplements are also being monitored to improve general fitness and conditioning levels. NAD+ metabolises fatty acids and glucose, which muscles utilise to support their structure and remain healthy.
• Repairs DNA : NMN creates NAD+, which can trigger sirtuins - which play an important role in maintaining DNA integrity. A study found that giving activated sirtuins could stabilise telomeres, reduce DNA damage and contribute to the reduction of liver disease .
• Improves eye function : lower levels of NAD+ have been shown to contribute to neurodegeneration in the eye and eyesight loss. By replenishing NAD+, it should be achievable to decrease this decline and improve vision . 
• Improves mitochondria function : We cannot live without mitochondria - and it cannot live without NAD+. These cell powerhouses are vital for metabolism and converting molecules from the food we eat into energy.
• Protects against diabetes : low in sulin sensitivity levels are a precursor to type 2 diabetes. Here, the body becomes less reactive to in sulin levels in the bloodstream, which can raise the risks of gaining weight and, ultimately diabetes. 
• Better brain function : scientists discovered that dispensing the NMN molecule in mice helps blood vessel dilation, which improves brain blood flow to help it function more effectively. 
• Fights obesity : NMN has also been linked to lower levels of obesity. One study found that a three-week NMN treatment in mice resulted in improved liver and plasma triglyceride levels, reduced fat mass and better glucose tolerance.
• Heart function : the human heart continues at a steady pace throughout your life and consumes a massive amount of energy for which it depends on NMN. A study uncovered that treating older mice with NMN and SS-31 could improve heart function
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Wuhan Yiruo Pharmaceutical Technology Co., Ltd.  was founded in 2023 and We are comprehensive enterprise with business range covering R&D, production and sales of APIs, pharmaceutical intermediates, plant extracts, all kinds of organic intermediates and so on. We bought 14,000 square meters production base in Panhu Industrial Park, established several pharmaceutical synthesis production lines, and continually expands our production capacity.

We have a professional research team of highly qualified and experienced chemists. most of our R&D team are Master and higher. With their effort, we quickly transfer the science fruit into production. Our manufacturing site is located in Wuhan which is equipped with 100L~5000L reactors; we can offer one-stop services from R&D to commercial production. (Normal reaction/ High-pressure reaction/ Catalytic reaction/ Low-Temperature reaction).

Q1.How to confirm the Product Quality before placing orders?

A. Offering you our products specification standard (tested by HPLC, UV, GC and TLC etc.)
B. Free samples could be sent to check the product quality before ordering.
C. If you have special requirement on the product, we may customize it according to your requirement until to your approval.

Q2: Samples & MOQ

A. We could provide some free samples, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier
to collect the samples.
B. For the high value product, our MOQ starts from 1g and generally starts from 10g.For other low value product, our MOQ starts from 1kg.

Q3: How about delivery?

A: Delivery lead time: within 1-2 days when get the payment.
B. Samples: please expect 5-7 days by FedEx,EMS, UPS,TNT..
C.Double customs clearance ,safe delivery ,gurantee receive.