DESCRIPITION:
Product Name: Indometacin
Synonyms: 1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid;indomethacin crystalline;indomethacin metha nol solution;indomethacin usp;AURORA KA-6542;INDOCIN;INDOMETACIN;INDOMETACINE
MF: C19H16ClNO4
MW: 357.79
Melting point: 155-162 °C
Boiling point: 499.4±45.0 °C
Density: 1.2135
Storage temp.: Store at RT
Appearance: White Powder
Description:
Aqueous solutions of indomethacin are not stable because of the ease of hydrolysis of the p-chlorobenzoyl group. The original synthesis of indomethacin by Shen et al. involved the formation of 2-methyl-5-methoxyindole acetic acid and subsequent acylation after protection of the carboxyl group as the t-butyl ester. It was introduced in the United States in 1965. It is still one of the most potent NSAIDs in use. It also is a more potent antipyretic than either aspirin or acetaminophen, and it possesses approximately 10 times the analgetic potency of aspirin.
Uses:
1.The product is anti-inflammatory, and antipyretic effect is obvious, mainly is used for salicylates to tolerance or the effect is not significant rheumatism and arthritis, ankylosing light spondylitis, osteoarthritis.
2.Non steroid anti-inflammatory analgesic
Product Name |
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CAS No . | |
EINECS NO. | |
MW | 357.79 |
Molecular F ormula | C19H16ClNO4 |
Chemical Property | White Fine Powder |
Purity(%) | >= 99% |
M elting Point | 155-162 °C |
Boiling Point | 499.4±45.0 °C(Predicted) |
Density | 1.2135 (rough estimate) |
Shelf Time | 24 months when properly stored |
HS CODE | 2933990099 |
Synonyms | 1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid;indomethacin crystalline;indomethacin meth anol solution;indomethacin usp ;aurora ka-6542;indocin;indometacin;indometacine |
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