4′ -Methoxyacetophenone; PARA Methoxyl Acetophenone; CAS100-06-1

Colour
White
Shelf Life
2-3 Years
Lead Time
5-7 Working Days
Transport
Air/Express/Sea
MOQ
10g
Site Audit
Available
Certificates
ISO9001/SGS
Stocks
in Stock
Package
1kg/5kg/10kg/25kg
Purity
99%
Samples
Available
Transport Package
Drum/Bottle/Bags
Trademark
Yunbang
Origin
China
Reference Price
Please contact us for quote
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Product Description

4′-Methoxyacetophenone;Para Methoxyl Acetophenone;CAS100-06-1
 
4′ -Methoxyacetophenone; PARA Methoxyl Acetophenone; CAS100-06-1
 
4'-Methoxyacetophenone Chemical Properties
Melting point  36-38 °C (lit.)
Boiling point  152-154 °C/26 mmHg (lit.)
density  1.08
FEMA  2005 | ACETANISOLE
refractive index  1.5470 (estimate)
Fp  >230 °F
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  H2O: soluble2.474g/L at 20°C
form  Crystals or Crystalline Powder
color  White
Water Solubility  insoluble
Sensitive  Light Sensitive
JECFA Number 810
BRN  742313
InChIKey NTPLXRHDUXRPNE-UHFFFAOYSA-N
CAS DataBase Reference 100-06-1(CAS DataBase Reference)
NIST Chemistry Reference Acetophenone, 4'-methoxy-(100-06-1)
EPA Substance Registry System 4'-Methoxyacetophenone (100-06-1)
 
Safety Information
4'-Methoxyacetophenone Usage And Synthesis
Identification
CAS.No.: 
100-06-1 
FL.No.: 
7.038
FEMA.No.: 
2005
NAS.No.: 
2005
CoE.No.: 
570
EINECS.No.: 
202-815-9 
JECFA.No.: 
810
 
 
Description Yellowish-white crystals with an odor similar to that of p-methylacetopheneone, suggestive of hawthorn and floral note of heliotrope, possessing a bitter and unpleasant taste. Useful in vanilla, nut, tobacco and butter flavors.
Regulatory Status CoE: Approved. Bev.: 10 ppm; Food: 20 ppm
FDA: 21 CFR 172.515
FDA (other): n/a
JECFA: ADI: Acceptable. No safety concern at current levels of intake when used as a flavoring agent (2001).
Usage Reported uses (ppm): (FEMA, 1994)
Food Category 
Usual 
Max. 
Alcoholic.beverages 
0.0001
0.0001
Baked.goods 
1.5
2
Chewing.gum 
110
110
Frozen.dairy 
1
2
Gelatins,.puddings 
0.2
0.2
Hard.candy 
278.3
335
Meat.products 
100
100
Nonalcoholic.beverages 
7.8
150
Soft.candy 
2.1
31
Natural occurrence Reported found in European cranberry (Vaccinium oxycoccus L.), guava fruit (Psidium guajava L.), Vitis labrusca L., tomato, anise (Pimpinella anisum L.), mentha oils, grilled and roasted beef, sherry, cloudberry (Rubus chamaemorus L.), salted and pickled plums, Illicium verum and black chokeberry (Aronia melanocarpa ell.).
Chemical Properties WHITE CRYSTALS OR CRYSTALLINE POWDER
Chemical Properties 4-Methoxyacetophenone occurs in anise oil. It forms white crystals (mp 38°C) with a sweet odor, reminiscent of hawthorn. 4-Methoxyacetophenone is prepared by Friedel-Crafts acetylation of ani sole. A modern process uses ??-zeolites as Friedel-Crafts catalysts in combination with a continuous flow technology. 4-Methoxyacetophenone is used in soap perfumes
Chemical Properties Yellowish-white crystals with an odor similar to that of p-methylacetopheneone, suggestive of hawthorn and floral note of heliotrope, possessing a bitter and unpleasant taste. Useful in vanilla, nut, tobacco and butter flavors
Occurrence Reported found in European cranberry (Vaccinium oxycoccus L.), guava fruit (Psidium guajava L.), Vitis labrusca L., tomato, anise (Pimpinella anisum L.), mentha oils, grilled and roasted beef, sherry, cloudberry (Rubus chamaemorus L.), salted and pickled plums, Illicium verum and black chokeberry (Aronia melanocarpa ell.).
Uses 4'-Methoxyacetophenone is a solid, pale yellow flavoring agent with a hawthornlike odor. It is soluble in most fixed oils and prop ylene glycol, and it is insoluble in glycerin and mineral oil. It is obtained by chemical synthesis. This flavoring substance or its adjuvant may be safely used in food in the minimum quantity required to produce its intended flavor. It can be used alone or in combination with other flavoring substances or adjuvants. It is also termed p-methoxyacetophenone.
Uses Perfumery (for floral odors), flavoring.
Definition ChEBI: A member of the class of acetophenones that is acetophenone substituted by a methoxy group at position 4.
Preparation From aniso le and ac etyl chlor ide in the presence of aluminum chloride and carbon disulfide; from anis ole and acetic acid in the presence of b oron trif luoride.
Taste threshold values Taste characteristics at 10 ppm: sweet, anisic, fruity, cherry with powdery vanilla nuances.
Synthesis Reference(s) The Journal of Organic Chemistry, 46, p. 5414, 1981  DOI:   10.1021/jo00339a036
Synthetic Communications, 26, p. 291, 1996  DOI:   10.1080/00397919608003617
Tetrahedron Letters, 35, p. 9471, 1994  DOI:   10.1016/S0040-4039(00)78574-1
Safety Profile Moderately toxic by ingestion. Human systemic effects by inhalation: pulse rate increase without fall in blood pressure and blood pressure elevation. A skin irritant. Flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES.
Purification Methods Crystallise the ketone from diethyl ether/pet ether. [Beilstein 8 IV 340.]
 
4′ -Methoxyacetophenone; PARA Methoxyl Acetophenone; CAS100-06-1
4′ -Methoxyacetophenone; PARA Methoxyl Acetophenone; CAS100-06-1 4′ -Methoxyacetophenone; PARA Methoxyl Acetophenone; CAS100-06-1 4′ -Methoxyacetophenone; PARA Methoxyl Acetophenone; CAS100-06-1
Company Informations:

Hunan Yunbang Pharmaceutical Co., Ltd. ( Yunbangpharm) located in Changsha High-tech Industrial Park, Hunan. It is a high-tech enterprise specializing in the research and development, production and sales of Pharmaceutical raw materials, Pharmaceutical intermediates(API) and Fine chemicals. Based in China, Yunbangpharm has been providing suitable solutions for many domestic,foreign pharmaceutical companies and traders. Excellent quality, good reputation and authentic price have won the praise of the majority of customers.
The company adheres to the corporate tenet of "We do not produce medicines, but help pharmaceutical companies make good medicines".

We can provide customers with customized processing, research and development services;
We can develop high-end Pharmaceutical and chemical products with high technical difficulties,high barriers and unique production processes;
We can provide 100 grams Grade, kilograms, and hundred kilograms of raw material pharmaceutical intermediates and other products.
We can perform -100°C to 300°C reaction.

R&D strength is the company's core competitiveness.Yunbangpharm has maintains a good cooperation relationship with many Universities and Research institutes locally, which can quickly transform R&D results into industrial production.

Our goal : To achieve the integrated upgrade of P harmaceutical intermediates, raw materials and high-end chemical products, adhere to "serving pharmaceutical companies, creating our brands" to provide customers with high-quality and low-cost pharmaceutical and chemical products, realizing Win-win cooperation and common development.

 

Organic Intermediate

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