Tacrolimus Powder of The Highest Quality CAS 104987-11-3

Model NO.
Lingding113
Colour
White
MW
804.02
Transport Package
Based on Customer′s Needs
Specification
1kg
Trademark
Lingding
Origin
Hebei, China
Production Capacity
9000 Kilogram/Kilograms Per Month
Reference Price
$ 13.50 - 540.00
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Product Description

Tacrolimus Powder of The Highest Quality CAS 104987-11-3
Product Description

Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. Tacrolimus was first extracted from the fermentation broth of Streptomyces tsukuba, a soil microbe found in Tsukuba, Japan.1 The name tacrolimus is derived by taking the 't' for Tsukuba, the name of the mountain where the soil sample was extracted, 'acrol' for macrolide and 'imus' for immunosuppressant. [2]  Although structurally unrelated to cyclosporin, tacrolimus shows a similar spectrum of immunosuppressive effects to this agent at the cellular and molecular level. Initial studies indicated that tacrolimus was a powerful immunosuppressant, displaying approximately 100-fold greater in vitro potency than cyclosporin in inhibiting T cell activation. Subsequent in vivo studies have shown tacrolimus to be effective both in suppressing spontaneous and experimental autoimmune disease, and in preventing allograft and xenograft rejection in animal models of organ transplantation.
Initially, tacrolimus was used for systemic immunosuppression of patients who had undergone allograft transplants to stop them from rejecting their new grafts. Soon, however, through the benefit of the serendipity of science, it was noticed that tacrolimus could produce favorable results in skin disorders in some of the patients who had undergone transplantation. The discovery of tacrolimus has thus lead to greater understanding of skin pathology, for example of atopic dermatitis. [3]  Subsequently, other topical applications of tacrolimus were reported and the use of this agent in dermatology is gradually expanding.
Product Name: Tacrolimus
CAS: 104987-11-3
MF: C44 H69 N O12
MW: 804.02
Melting Point: 113-115ºC
EINECS: 1308068-626-2
Tacrolimus Powder of The Highest Quality CAS 104987-11-3
Tacrolimus Powder of The Highest Quality CAS 104987-11-3



Company Information
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise,  The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market.  Welcome domestic and foreign customers to negotiate.

Tacrolimus Powder of The Highest Quality CAS 104987-11-3
Tacrolimus Powder of The Highest Quality CAS 104987-11-3
Our Services
 1.Any inquiry or message will be replied within 12 hours.
 2.Professional manufacturer. Welcome to visit our website.
 3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
 4.Fast delivery.
 5.After-sale services

Packaging & Shipping
                         Shipping Terms                                                   
By Express   By Air By Sea
Suitable for under 50kg
 Fast: 3-7 days
 
 Door to door service,
   easy to pick up the goods 		      Suitable for more than 50kg
      Fast: 3-7 days
      High cost
      Port to port, 
      professional broker needed 		    Suitable for more than 500kg
    Slow: 7-45 days
    Low cost
    Port to port, 
    professional broker needed

Tacrolimus Powder of The Highest Quality CAS 104987-11-3
Tacrolimus Powder of The Highest Quality CAS 104987-11-3 Tacrolimus Powder of The Highest Quality CAS 104987-11-3

 

Organic Intermediate

PNEUTEC.IT, 2023