China GMP Quality Peptides Raw Powder Factory Supply 99% Purity Sams Peptide CAS: 125911-68-4
Product Description
| Product Name | SAMS Peptide |
| CAS NO | 125911-68-4 |
| Molecular Formula | C74H131N29O18S2 |
| Molecular Weight | 1779.2 |
| Density | 1.47±0.1 g/cm3(Predicted) |
| Solubility | DMF: 15 mg/ml;DMSO: 15 mg/ml;Ethanol: 1 mg/ml;PBS (pH 7.2): 10 mg/ml |
| Purity | ≥95% |
| Grade | Phamaceutical Grade |
| Appearance | White to Off-white Powder |
| Storage | Desiccate at -20°C |
AMP-activatedproteinkinase plays a role in energy metabolism and glucose homeostasis by monitoring the ratio of ATP to AMP. This kinase can inactivate HMG-CoA reductase and acetyl-CoA carboxylase as well as block the activation of hormone-sensitive lipase by cyclic-AMP-dependent protein kinase (protein kinase A or PKA). SAMS peptide is a synthetic peptide substrate for AM/PK based on the sequence around Ser79 (which is phosphorylated exclusively by AM/PK) on acetyl-CoA carboxylase.1 In this sequence, Ser77 (which is phosphorylated exclusively by PKA) is replaced by alanine to eliminate a neighboring binding site for PKA.1 This substitution yields a substrate more specific for AM/PK than acetyl-CoA carboxylase itself. SAMS peptide is phosphorylated rapidly by AM/PK, providing a convenient and sensitive tool for assaying AM/PK activity.
For obtaining a higher solubility , please warm the tube at 37 ºC and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20ºC for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20ºC. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
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