Product name | Cephradine |
CAS No. | 38821-53-3 |
Molecular formula | C16H19N3O4S |
Molecular weight | 349.4 |
Purity | 99% |
Appearance | White or almost white powder |
Package | Aluminum Bag;Drums |
Shelf life | 2 years |
Test Items |
Specification |
Result |
Description |
White or slightly yellow crystalline powder |
Conforms |
Solubility |
Sparingly soluble in water, practically insolublein alcohol |
Conforms |
Identification |
Conforms |
Conforms |
Appearance of solution |
Solutions is not more opalescent than referencesuspension II |
Conforms |
Clearance of solution |
Clear |
Clear |
Absorbance at 450nm |
Not more than 0.2 |
0.045 |
PH |
Between3.5 and 6.0 |
4.9 |
Specific Optical Rotation |
Between +80and +90on anhydrous basis |
+85.9 |
Absorbance at 330nm |
Not more than 0.050 |
0.007 |
Specific Absorbance at 262nm |
Between 215 to 240 on anhydrous basis |
226 |
Particle size |
6-14%≥40 mesh, 60-80% between 100-40 mesh, 15-25%≤100mesh |
Confirms |
Related substances: 7-ADCA Cyclohexa-1, 4-dienylglycine Any other impurity |
Not more than 1.0% by TLC Not more than 1.0% by TLC Not more than 1.0% by TLC |
Confirms Confirms Confirms |
Water |
Not more than 6.0% |
4.5% |
Cephalexin content |
Not more than 5.0% |
1.0% |
Sulfated Ash |
Not more than 0.20% |
0.06% |
Loose Density |
0.62-0.68 GR/ML |
0.65GR/ML |
Tapped Density |
≥0.85 GR/ML |
Confirms |
Assay |
Not less than 90.0% w/w as cefradine on anhydrousbasis by HPLC Between 95.0% and 102.0% w/w on anhydrous basis byHPLC (sum of the percentage contents of cephradine) |
96.3% 99.2% |