Pyrimidinetetramine sulfate Usage And Synthesis |
Chemical Properties | Light yellow crystal powder |
Uses | Intermediate in the production of Methotrexate |
Uses | Intermediate in the production of Methotrexate. |
Purification Methods | Purify the salt by recrystallisation from H2O, 2N H2SO4 (20 parts, 67% recovery) or 0.1N H2SO4 (40 parts, 62% recovery), and dried in air. [UV: Konrad & Pfleiderer Chem Ber 103 722 1970, Malletta et al. J Am Chem Soc 69 1814 1947, Cavalieri et al. J Am Chem Soc 70 3875 1948, Beilstein 25 H 423, 25 III/IV 3106.] |