| Product Name: | β-Estradiol |
| Synonyms: | BETA-ESTRADIOL-16,16,17-D3;17BETA-ESTRADIOL-16,16,17-D3;β-Estradiol, 99% (dry wt.), ca 3% water;1,3,5-Estratriene-3,17beta-diol;17beta-Estradiol;3,17beta-Dihydroxy-1,3,5(10)-estratriene;Dihydrofolliculin;Estradiol |
| CAS: | 50-28-2 |
| MF: | C18H24O2 |
| MW: | 272.39 |
| EINECS: | 200-023-8 |
| Product Categories: | powder or crystal;Inhibitors;Intermediates & Fine Chemicals;API;VIVELLE;Hormone Drugs;Analytical Chemistry;Biochemistry;Environmental Endocrine Disruptors;Estradiol, etc. (Environmental Endocrine Disruptors);Hydroxysteroids;Intracellular receptor;Pharmaceuticals;Steroid and Hormone;Steroids;Estrogen;Hormone |
| Mol File: | 50-28-2.mol |
| β-Estradiol Chemical Properties |
| Melting point | 178-179 °C(lit.) |
| alpha | D25 +76 to +83° (dio-xane) |
| Boiling point | 355.44°C (rough estimate) |
| density | 1.0708 (rough estimate) |
| refractive index | 80.4 ° (C=1, Dio-xane) |
| Fp | 2ºC |
| storage temp. | room temp |
| solubility | Practically insoluble in water, soluble in ace-tone, sparingly soluble in ethanol (96 per cent) |
| form | powder |
| pka | pKa 10.71±0.02(H2O(0.1% p-dio-xane) t=25±0.1 I=0.03(KCl))(Approximate) |
| color | White to off-white |
| Water Solubility | Soluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, ace-tone, dio-xane and alkali hydroxides. Slightly soluble in vegetable oils. |
| Merck | 14,3703 |
| BRN | 1914275 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | VOXZDWNPVJITMN-ZBRFXRBCSA-N |
| CAS DataBase Reference | 50-28-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Estra-1,3,5(10)-triene-3,17beta-diol(50-28-2) |
| EPA Substance Registry System | Estradiol (50-28-2) |
| Safety Information |
| Hazard Codes | T,Xn,F |
| Risk Statements | 60-61-45-63-64-40-36-20/21/22-11-48 |
| Safety Statements | 53-22-36/37/39-45-36/37-26-16-36-20 |
| RIDADR | 2811 |
| WGK Germany | 3 |
| RTECS | KG2975000 |
| F | 8-10 |
| HazardClass | 6.1 |
| PackingGroup | III |
| HS Code | 29372390 |
| Hazardous Substances Data | 50-28-2(Hazardous Substances Data) |
| Toxicity | LD50 subcutaneous in rat: > 300mg/kg |