CE, ISO9001 Approved Rad50 (A708) Polyclonal Antibody

Model NO.
BS2232
Host
Rabbit/Mouse
Reactivity
Human, Mouse, Rat
Certification
CE, ISO9001
Transport Package
Refrigerated Transport
Specification
100ug/1mg
Trademark
Bioworld
Origin
China
HS Code
300219000
Production Capacity
3000 Vials
Reference Price
$ 222.75 - 247.50
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Product Description

Catalog No. BS2232
Product Name Rad50 (A708) polyclonal antibody
Applications WB IHC
Alternative Name DNA repair protein RAD50; hRAD50; RAD50
Swiss-Prot Q92878
Host Rabbit
Reactivity Human,Mouse,Rat
Application_all WB: 1:500~1:1000 IHC: 1:50~1:200
Product Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity Rad50 (A708) polyclonal antibody detects endogenous levels of Rad50 protein.
BiowMW ~ 153 kDa
Note For research use only, not for use in diagnostic procedure.
Immunogen Synthetic peptide, corresponding to amino acids 670-722 of Human Rad50.

Background

Rad52 family members (Rad50, Rad51B/C/D, Rad52, Rad54, MRE11) mediate DNA double-strand break repair (DSBR) for DNA damage that otherwise could cause cell death, mutation or neoplastic transformation. Rad51 (RECA, BRCC5) interacts with BRCA1 and BRCA2 to influence subcellular localization and cellular response to DNA damage. BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis from deregulation of Rad51. Rad52 forms a heptameric ring that binds single-stranded DNA ends and catalyzes DNA-DNA interaction necessary for the annealing of complementary strands. CE, ISO9001 Approved Rad50 (A708) Polyclonal Antibody

CE, ISO9001 Approved Rad50 (A708) Polyclonal Antibody CE, ISO9001 Approved Rad50 (A708) Polyclonal Antibody CE, ISO9001 Approved Rad50 (A708) Polyclonal Antibody CE, ISO9001 Approved Rad50 (A708) Polyclonal Antibody CE, ISO9001 Approved Rad50 (A708) Polyclonal Antibody CE, ISO9001 Approved Rad50 (A708) Polyclonal Antibody CE, ISO9001 Approved Rad50 (A708) Polyclonal Antibody

 

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PNEUTEC.IT, 2023