Pyrantel pamoate (under US Pharmacopoeia) or Pyrantel Embonate (under European Pharmacopoeia), is used as a deworming agent in the treatment of hookworms (all species) and roundworms (Ascaris lumbricoides, aka ascarids in humans) in domesticated animals such as horses, cattle, sheep, pigs, cats, dogs, and many other species. It is a combination of pyrantel and pamoic acid. Some drug companies pair pyrantel pamoate with praziquantel for tapeworms, and sometimes febantel for whipworms in order to provide more complete treatment for intestinal parasites in one dose.
B atch N o . | HF1 611 18 | Q uantity | 1110kgs |
Mfg. Date | Nov .18 , 201 6 | Package | As required |
R ep . D ate | Nov .25 , 201 6 | E xp . D ate | Nov .17 , 201 8 |
I tems | S tandards | R esults | |
Appearance | White or off-white amorphous,odorless,hygroscopic powder | Complies | |
I dentification | B y IR | Complies | |
B y UV | Complies | ||
B y TLC | Complies | ||
By Masculine reaction | Complies | ||
Specific Rotation | -0.5°~+0.5° | 0° | |
Water Content | ≤ 3.00 % | 1.50% | |
H eavy M etal | ≤ 1 0ppm | Complies | |
Free Aromatic Amine | ≤0. 05 % | 0.01% | |
Free Iodine | Complies with standard | Complies | |
Free Iodide | ≤0. 001 % | ND | |
Ionic Compounds | ≤0. 01 % | ND | |
Residual Solvent | Isopropyl alcohoil ≤ 50ppm | 1ppm | |
Methanoil ≤ 50ppm | 1ppm | ||
Methoxyethanol ≤ 20ppm | 2ppm | ||
N-Butanoil ≤ 50ppm | 1ppm | ||
3-Chloro-1,2-propanedio ≤ 25ppm | ND | ||
Color Of Solution | 400nm: ≤ 0.180 | 0.137 | |
420nm ≤ 0.030 | 0.006 | ||
450nm ≤ 0.015 | 0.000 | ||
R ela ted S ubstance | Impurity A: ≤0. 30 % | 0.14% | |
O-alkylated compounds: ≤ 0.50% | 0.48% | ||
Any individual impurity: ≤ 0.10% | 0.04% | ||
The total impurities: ≤ 0.30% | 0.13% | ||
A
ssay
(HPLC,basis on drying) |
98.5% ~102.0% | 99.10% |
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