Naproxen is synthesized from 2-methoxynaphthalene and the (+)-isomer obtained by resolution with cinchonidine (61). It was introduced in the United States in 1976 and, as a generic drug, has consistently been among the more popular NSAIDs. It is marketed as the S-(+)-enantiomer, but interestingly, the sodium salt of the (-)-isomer also is on the market as Anaprox. As an inhibitor of prostaglandin biosynthesis, it is 12 times more potent than aspirin, 10 times more potent than phenylbutazone, three to four times more potent than ibuprofen, and four times times more potent than fenoprofen, but it is approximately 300 times less potent than indomethacin.
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Product Name
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Naproxen |
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CAS
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22204-53-1 |
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Appearance
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White crystalline powder |
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MF
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C14H14O3 |
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Molecular Weight
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230.26 |
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Purity
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99%
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Storage
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Keep in a cool, dry, dark location in a tightly sealed container or cylinder
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Shelf Life
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24 Months
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Test |
Standards |
Results |
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Characteristics |
A white crystalline powder |
White crystalline powder |
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Solubility |
Easily soluble in aceton, soluble in methano, ethanol, glacial acetic acid, hardly soluble in benzen, almost insoluble in water |
Conforms |
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Identification |
Positive |
Conforms |
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Melting range |
152~154 °C |
155.3°C |
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Chloride |
Not more than 0.014% |
<0.014 % |
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Sulphate |
Not more than 0.02% |
<0.02% |
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Sulfide |
No coloration or spotting occurs |
Conforms |
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Readily carbonizable substances |
Conforms |
Conforms |
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Free P-aminophenol |
Not more than 0.005% |
<0.005 % |
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Related substance |
Conforms |
Conforms |
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Loss on drying |
Not more then 0.5% |
0.06% |
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Residue on ignition |
Not more then 0.1% |
0.03% |
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Assay |
99.0~101.0% |
99.6% |
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Heavy metals |
Not more than 0.001% |
<0.001% |
It is a non-steroidal anti-inflammatory drug for the relief of fever and inflammation and pain associated with arthritis or other symptoms , it has anti-inflammatory, antipyretic and analgesic effects. Naproxen plays a role by inhibiting the cyclooxygenase, which generates prostaglandin and is one kind of enzymes related to inflammatory mediators . It is recommended to take the drug during meals to reduce stomach irritation.
| Name | CAS No. | Purity |
| Sunifiram | 314728-85-3 | 99.0% |
| Unifiram | 99.0% | |
| Idebenone | 99.0% | |
| Pramiracetam | 68497-62-1 | 99.0% |
| Fasoracetam | 110958-19-5 | 99.0% |
| Oxiracetam | 62613-82-5 | 99.0% |
| Phenylpiracetam hydrazide | 77472-71-0 | 99.0% |
| Galantamine Hydrobromide | 69353-21-5 | 98.0% |
| Tianeptine | 66981-73-5 | 99.0% |
| Tianeptine sodium | 30123-17-2 | 99.0% |
| Tianeptine hemisulfate monohydrate (THM) | 1224690-84-9 | 99.0% |
| 9-ME-BC(9-Methyl-9H-beta-carboline) | 2521/7/5 | 99.0% |
| Agomelatine | 138112-76-2 | 99.0% |
| 6-Paradol 98% | 27113-22-0 | 98% Oil form |
| 6-Paradol 50% | 27113-22-0 | 50% Powder form |
| Nicotinamide Riboside Chloride(NRC) | 23111-00-4 | 98.0% |
| Beta-Nicotinamide Mononucleotide(NMN) | 1094-61-7 | 99.0% |
| β-Nicotinamide Adenine Dinucleotide(NAD+) | 53-84-9 | 98.0% |
| Noopept ,GVS-111 | 157115-85-0 | 99.0% |
| Piracetam | 7491-74-9 | 99.0% |
| Phenibut | 1078-21-3 | 99.0% |
| Coluracetam | 135463-81-9 | 99.0% |
| N-Methyl-D-aspartic acid(NMDA) | 6384-92-5 | 99.0% |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 99% Powder form |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 50% Graininess form |
| Citicoline | 987-78-0 | 99.0% |
| PRL-8-53 | 51352-87-5 | 98.0% |
| NSI-189 Phosphate | 1270138-41-4 | 99.0% |
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