PNEUTEC.IT
Pharmaceutical Intermediate
Supply Veterinary API Powder CAS 1397 -89-3 Amphotericin B
Model NO.
TY-02AL
Einecs
616-396-9
Shelf
2 Years
Assay
99%
Appearance
White Powder
CAS No.
1397-89-3
Transport Package
25kg/Drum 1g,10g,100g,500g,1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
$ 27.00 - 54.00
Contact Us
Description
Product Description
Product name
Amphotericin B
CAS
1397-89-3
Appearance
white powder
Assay
99%
Storage
Cool and Protect from light
Product Name:Amphotericin B
CAS:1397-89-3
MF:C47H73NO17
MW:924.08
EINECS:215-742-2
Mol File:1397-89-3.mol
Melting point:>170°C
alpha D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)
Boiling point:804.34°C (rough estimate)
Density 1.34
refractive index 1.5280 (estimate)
storage temp. 2-8°C
solubility sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20?#x00b0;C. Stable at 37?#x00b0;C for 3 days.
pkapKa ~5.7(DMF/H2O) (Uncertain)
form powder
color yellow
Water Solubility <0.1 g/100 mL at 21 ºC
Description
Amphotericin B is a polyene macrolide antibiotic which was introduced into clinical medicine in 1955. It is primarily used for the treatment of serious systemic fungal infections. It is also used as an alternative drug for the treatment of drug resistant Leishmania. Amphotericin B is an effective drug, but its use is limited because of its toxicity. The advent of liposome encapsulated amphotericin may increase its use in multiresistant Leishmania in the future[1].
The mechanism of action of amphotericin is as yet not clear. In mycosis it binds to ergosterol present in fungal cell membranes. As a result, the drug forms pores or channels on the cell membrane which disturbs the membrane function allowing electrolytes (particularly potassium) and small molecules to leak from the cell resulting in cell death [2]. Oxidative damage to the cell may also be involved in this process [3]. Its mechanism of action in leishmaniasis may be similar to that in fungi.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company phiosophy of integrity, professionalism, quality first, and
customer service. With the efforts of all the company's employees, it has established long-term
and stable cooperative relations with many domestic and foreign customers, and won the unanimous trust of domestic
and foreign customers. With good comments, our company have made great progress.
Our company takes pioneering and innovative, high-quality and efficient as the code of conduct, and strives to provide
customers with efficient services,
high-quality products, and reasonable prices. We have established a customer demand-oriented, flexible, diverse and customizable service according to the different needs of different customers. Mode, and ultimately achieve the goal of
win-win.
Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.
Pharmaceutical Intermediate
Auto Parts Suspension Control Arm Bushing OEM 48061 -26031 for Hiace Rzh10 Tacoma II Pickup
Solar Hybrid Single Phase MPPT 5kVA Tie Grid Inverter
5kw Hybrid Solar Inverter Built-in 15A MPPT Solar Charge Controller with Battery
Factory Wholesale 99% CAS108 91 8 with Best Price
Anka Rack and Pinion Construction Inclined Hoist
Auto 4-Wire for Subaru O2 Oxygen Sensor 22641 -AA032 Liberty Outback Ez30 3.0L Lambda Sensor
87641 SAE Split Swaged Flange Branch Fitting
Non-Aligning Bearings Unseparated Jrzc or Customzied Shandong, China 608zz Bearing
Jtc Tool Vmc Machine CNC Milling 1150 Wholesale Heavy Duty Machining Center China Supplier Vmc Machine Price 0.03-0.04mm Processing Precision CNC Machine Vmc850
Metoprololtar 56392 -17-7 Hypertension/high blood pressure/heart failure treatment
CF-033 Replacement Kits Set for Fuel Injector (orings)
High Quality Acrylic Polymer Emulsion for Alkali Resistant Back Cove for Construction Industry
Professional Production Factory S355j2 20mm Carbon Steel Round Bar
15 Inch Silver Round LED Ceiling Light with White Glass (LED-15212-14)
43045 -1612 Wire to Board Molex Connector 16 Pin
Hot Selling Polyester Durable Waterproof Mesh Fabric for Custom
PNEUTEC.IT, 2023