Histone H3 (DiMethyl K4) Polyclonal Antibody

Model NO.
BS69023
Specification
100ug/1mg
Trademark
Bioworld
Origin
China
Production Capacity
3000 Vials
Reference Price
$ 222.75 - 247.50
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Product Description

Catalog No. BS69023
Product Name Histone H3 (DiMethyl K4) polyclonal antibody
Applications WB
Alternative Name Hist1h3a; Hist1h3b; H3 histone family; member A; H3/A; H31; H3FA; Hist1h3a; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; histone 1; H3a; Histone cluster 1; H3a; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l
Swiss-Prot P68431    Q71DI3    P84243    Q6NXT2   
Host Rabbit
Reactivity Human,Mouse,Rat
Application_all WB: 1:500~1:1000 IHC: 1:50~1:200
Product Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity Histone H3 (DiMethyl K4) polyclonal antibody detects endogenous levels of Histone H3 protein.
BiowMW ~ 17 kDa
Note For research use only, not for use in diagnostic procedure.
Immunogen Synthetic peptide, corresponding to Human Histone H3.

  • Western blot (WB) analysis of Histone H3 (DiMethyl K4) polyclonal antibody at 1:500 dilution LaneA:U20S whole cell lysate LaneB:DLD whole cell lysate

Background

In eukaryotes, DNA is wrapped around histone octamers to form the basic unit of chromatin structure. The octamer is composed of histones H2A, H2B, H3 and H4, and it associates with approximately 200 base pairs of DNA to form the nucleosome. The association of DNA with histones results in dense packing of chromatin, which restricts proteins involved in gene transcription from binding to DNA. p300 preferentially acetylates Histone H3 at lysines 14 and 18 and Histone H4 at lysines 5 and 8. PCAF in its native form, primarily acetylates Histone H3 at lysine 14 to a monoacetylated form, and less efficiently acetylates Histone H4 at lysine 8. Histone H4 may also be acetylated at lysines 12 and 16, and the involvement of acetylated H4 with Histones H2A, H2B and H3 suggests that acetylated histones may be involved in dynamic chromatin remodeling. Histone H3 (DiMethyl K4) Polyclonal Antibody
Histone H3 (DiMethyl K4) Polyclonal Antibody Histone H3 (DiMethyl K4) Polyclonal Antibody Histone H3 (DiMethyl K4) Polyclonal Antibody

 

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PNEUTEC.IT, 2023