CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride

Model NO.
TY-02ALI
Einecs
616-396-9
Shelf
2 Years
Assay
99%
Appearance
White Powder
CAS
25316-40-9
Transport Package
25kg/Drum 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
Please contact us for quote
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Product Description

CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride
CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride

CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride
 
Product name Doxorubicin hydrochloride
CAS 25316-40-9
Appearance white powder
Assay 99%
Storage Cool and Protect from light


CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride

Product Name:Doxorubicin hydrochloride
CAS:25316-40-9
MF:C27H30ClNO11
MW:579.98
EINECS:246-818-3
Mol File:25316-40-9.mol  
Melting point:216 °C (dec.)(lit.)
alpha D20 +248±2° (c = 0.1 in methanoll)
storage temp. 2-8°C
solubility H2O: 10 mg/mL, clear, red-orange
pkapKa 8.25±0.60 (Uncertain);8.43±0.70 (Uncertain);11.9±0.4 (Uncertain);12.95±0.1 (Uncertain);13.8±0.70 (Uncertain)
form solid
color orange to dark red
Water Solubility Soluble in water.


CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride
Description
Doxorubicin (DXR) is a clinically important cancer chemotherapeutic agent and, in spite of undesirable acute and long-term toxic effects, DXR remains one of the most widely used antitumor drugs because of its broad spectrum of activity[1]. DXR was first isolated in 1969[1] from Streptomyces peucetius subsp caesius ATCC 27952, a higher DXR-producing mutant strain derived from the wild-type S. peucetius ATCC 29050 strain, and is formed by C-14 hydroxylation of its immediate precursor, DNR. Although a number of organisms (including the 29050 strain) are known to produce DNR [2], S. peucetius subsp caesius is the only organism reported to produce DXR. The current production of DXR is over 225 kilograms annually due to its wide use and the fact that it is the starting point for the synthesis of numerous analogs and derivatives aimed at improving clinical cancer treatment[1]. Although DXR was discovered as a microbial metabolite, it is produced commercially by semi-synthesis from the more abundant DNR instead of by fermentation. High-DNR producing strains are available worldwide yet apparently lack the ability to make useful amounts of DXR or the DXR produced cannot easily be separated from the DNR that also is present. Consequently, the development of improved strains for DXR production is a beneficial goal since this drug is an expensive product.


GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
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Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
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CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride CAS 25316-40-9 Doxorubicin HCl / Doxorubicin Hydrochloride

 

Pharmaceutical Intermediate

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